STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0429Similar to Mycobacterium leprae polyprenyl diphosphate synthase component ML2277 TR:Q9CBA5 (EMBL:AL583925) (330 aa) fasta scores: E(): 1.6e-57, 51.69% id in 325 aa, and to Bacillus stearothermophilus heptaprenyl diphosphate synthase component II HepT or HepS-2 SW:HEP2_BACST (P55785) (320 aa) fasta scores: E(): 9.6e-33, 38.99% id in 318 aa. (330 aa)    
Predicted Functional Partners:
uppS2
Putative undecaprenyl phosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
 
 0.974
DIP1612
Similar to Mycobacterium aurum geranylgeranyl pyrophosphate synthase GgpP TR:Q9K567 (EMBL:AJ133724) (371 aa) fasta scores: E(): 1.5e-36, 39.09% id in 353 aa, and to Sulfolobus acidocaldarius geranylgeranyl pyrophosphate synthetase Gds SW:GGPP_SULAC (P39464) (330 aa) fasta scores: E(): 3.1e-11, 28.49% id in 358 aa.
  
  
 
0.925
DIP0428
Similar to Mycobacterium leprae putative FAD-linked oxidoreductase ML2276 TR:Q9CBA6 (EMBL:AL583925) (408 aa) fasta scores: E(): 7.2e-61, 54.47% id in 391 aa.
  
 
 0.752
uppS1
Putative undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
  
 0.732
DIP1870
Putative phytoene synthase; Similar to Agrobacterium aurantiacum phytoene synthase CrtB SW:CRTB_AGRAU (P54975) (301 aa) fasta scores: E(): 6.8e-09, 29.57% id in 284 aa, and to Corynebacterium glutamicum phytoene synthase CrtB TR:AAK64298 (EMBL:AF159510) (304 aa) fasta scores: E(): 1.1e-51, 51.22% id in 285 aa.
  
 
 0.700
rnj
Conserved hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
  
    0.636
idi
Isopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
  
  
 0.604
DIP0427
Similar to Clostridium acetobutylicum lactate dehydrogenase CAC3552 TR:AAK81477 (EMBL:AE007851) (320 aa) fasta scores: E(): 1.6e-36, 38.6% id in 316 aa, and to Bacillus subtilis L-lactate dehydrogenase Ldh or LctE SW:LDH_BACSU (P13714) (320 aa) fasta scores: E(): 2.9e-25, 33.95% id in 324 aa; Belongs to the LDH/MDH superfamily.
     
 0.551
ndk
Putative nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
 
 
 0.495
menH
Putative ubiquinone/menaquinone biosynthesis methlytransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
 
  
 0.458
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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