Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
narKPutative nitrate/nitrite transport system integral membrane protein; Similar to Thermus thermophilus NarK1 TR:Q9RA46 (EMBL:AJ237974) (435 aa) fasta scores: E(): 2e-64, 59.56% id in 418 aa, and to Escherichia coli nitrite extrusion protein 1 NarK or B1223 SW:NARK_ECOLI (P10903) (463 aa) fasta scores: E(): 5.2e-17, 27.63% id in 427 aa. (432 aa)    
Predicted Functional Partners:
narG
Similar to Escherichia coli respiratory nitrate reductase 1 alpha chain NarG or NarC or BisD or B1224 SW:NARG_ECOLI (P09152) (1246 aa) fasta scores: E(): 0, 46.16% id in 1237 aa; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 
 0.999
narH
Similar to Bacillus subtilis nitrate reductase beta chain NarH SW:NARH_BACSU (P42176) (487 aa) fasta scores: E(): 1.4e-114, 56.31% id in 499 aa.
 
 
 0.997
narI
Similar to Streptomyces coelicolor putative nitrate reductase gamma chain NarI TR:O86714 (EMBL:AL031515) (240 aa) fasta scores: E(): 1e-44, 49.78% id in 237 aa, and to Bacillus subtilis nitrate reductase gamma chain NarI SW:NARI_BACSU (P42177) (223 aa) fasta scores: E(): 6.2e-33, 42.27% id in 220 aa.
 
 
 0.996
DIP0501
Putative nitrate/nitrite transport system integral membrane protein; Similar to Thermus thermophilus Nark2 TR:Q9RA45 (EMBL:AJ237974) (443 aa) fasta scores: E(): 2e-79, 50.22% id in 448 aa, and to Escherichia coli nitrite extrusion protein 2 NarU or B1469 SW:NARU_ECOLI (P37758) (462 aa) fasta scores: E(): 1.2e-31, 33.47% id in 472 aa.
  
0.996
DIP1876
Putative multicopper oxidase; C-terminus is similar to an internal regions of Neisseria gonorrhoeae major anaerobically induced outer membrane protein Pan 1 AniA SW:ANIA_NEIGO (Q02219) (392 aa) fasta scores: E(): 3.5e-18, 30.1% id in 299 aa, and Neisseria meningitidis nitrite reductase, major outer membrane copper-containing protein NMA1887 TR:Q9JTB8 (EMBL:AL162757) (386 aa) fasta scores: E(): 3e-18, 30.43% id in 299 aa.
    
 0.902
DIP0498
Similar to Streptomyces coelicolor nitrate reductase delta chain NarJ3 TR:Q9EWF5 (EMBL:AL451182) (220 aa) fasta scores: E(): 3e-20, 39.39% id in 198 aa, and to Bacillus subtilis nitrate reductase delta chain NarJ SW:NARJ_BACSU (P42178) (184 aa) fasta scores: E(): 1.9e-12, 29.14% id in 175 aa.
 
  
 0.848
DIP0847
Hypothetical protein; No significant database matches.
   
    0.747
DIP1430
Putative phosphofructokinase (PTS system); Similar to Rhodobacter capsulatus 1-phosphofructokinase FruK SW:K1PF_RHOCA (P23386) (316 aa) fasta scores: E(): 1.2e-05, 32.6% id in 322 aa, and to Escherichia coli 6-phosphofructokinase isozyme 2 PfkB or B1723 SW:K6P2_ECOLI (P06999) (309 aa) fasta scores: E(): 0.00069, 30.51% id in 308 aa; Belongs to the carbohydrate kinase PfkB family.
   
    0.745
moaC
Similar to Streptomyces coelicolor molybdenum cofactor biosynthesis protein MoaC TR:Q9RKA8 (EMBL:AL132674) (170 aa) fasta scores: E(): 2.5e-29, 55.92% id in 152 aa, and to Escherichia coli, and molybdenum cofactor biosynthesis protein C MoaC or ChlA3 or B0783 or Z1002 or ECS0861 SW:MOAC_ECOLI (P30747) (160 aa) fasta scores: E(): 1.9e-19, 47.74% id in 155 aa.
  
  
 0.689
glnD
Similar to Corynebacterium glutamicum [protein-PII] uridylyltransferase GlnD SW:GLND_CORGL (Q9X706) (692 aa) fasta scores: E(): 7.1e-126, 52.6% id in 709 aa, and to Escherichia coli [protein-PII] uridylyltransferase GlnD or B0167 SW:GLND_ECOLI (P27249) (890 aa) fasta scores: E(): 1.1e-05, 25.76% id in 555 aa. Note It might have two alternative start codons at residues 3 or 4.
      
 0.631
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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