STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0511Conserved hypothetical protein (pseudogene; 1 probable transmembrane helix predicted for DIP0508 by TMHMM2.0; Belongs to the DapA family. (306 aa)    
Predicted Functional Partners:
DIP0519
Putative epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).
 
 
 0.973
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
 
 
 0.968
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
 
 0.945
DIP0513
Putative oligopeptide transport system (integral membrane and ATP-binding proteins); C-terminal region similar to Salmonella typhimurium oligopeptide transport ATP-binding protein OppD or STM1743 SW:OPPD_SALTY (P04285) (335 aa) fasta scores: E(): 3.2e-38, 42.07% id in 328 aa, and N-terminal region to Bacillus firmus dipeptide transport system permease protein DppC SW:DPPC_BACFI (P94312) (304 aa) fasta scores: E(): 4.2e-32, 41.19% id in 267 aa.
 
     0.935
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
  
 
0.926
thrA
Similar to Corynebacterium glutamicum homoserine dehydrogenase Hom or ThrA SW:DHOM_CORGL (P08499) (445 aa) fasta scores: E(): 4.2e-117, 75.28% id in 437 aa, and to Bacillus subtilis homoserine dehydrogenase Hom or Tdm SW:DHOM_BACSU (P19582) (433 aa) fasta scores: E(): 4.2e-54, 40.18% id in 433 aa.
    
 0.909
DIP0514
Similar to Bacillus subtilis oligopeptide transport system permease protein AppB SW:APPB_BACSU (P42062) (317 aa) fasta scores: E(): 4.6e-31, 34.7% id in 317 aa.
 
     0.872
DIP0515
Similar to Escherichia coli O157:H7 EDL933 putative transport protein Z1054 TR:AAG55204 (EMBL:AE005264) (512 aa) fasta scores: E(): 4.3e-19, 24% id in 479 aa. Note: Contains a putative twin-arginine translocation (TAT) system recognition motif (RRDFFK) at the N-terminal region.
 
     0.854
DIP0512
Similar to Bacillus subtilis oligopeptide transport ATP-binding protein OppF or Spo0KE SW:OPPF_BACSU (P24137) (308 aa) fasta scores: E(): 1.7e-36, 48.51% id in 235 aa.
 
     0.811
DIP1814
Similar to Corynebacterium glutamicum dihydrodipicolinate synthase DapA SW:DAPA_CORGL (P19808) (301 aa) fasta scores: E(): 7.7e-14, 29.25% id in 270 aa, and to Streptomyces coelicolor dihydrodipicolinate synthase SC9A10.08 SW:DAPA_STRCO (O86841) (299 aa) fasta scores: E(): 2.5e-13, 27.94% id in 272 aa; Belongs to the DapA family.
  
     0.715
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: low (30%) [HD]