STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0538Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 46.2 kDa protein SC5F8.10c TR:Q9K4L4 (EMBL:AL357613) (410 aa) fasta scores: E(): 2.1e-74, 50% id in 394 aa. (417 aa)    
Predicted Functional Partners:
tsaD
Putative endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
  
 0.980
DIP0539
Similar to Bacillus subtilis probable multiple sugar-binding transport ATP-binding protein MsmX SW:MSMX_BACSU (P94360) (365 aa) fasta scores: E(): 1.1e-54, 49.86% id in 367 aa; Belongs to the ABC transporter superfamily.
  
    0.695
DIP2107
Similar to Streptomyces coelicolor putative integral membrane transport protein SCD10.28c TR:Q9K3U9 (EMBL:AL359988) (550 aa) fasta scores: E(): 6.2e-18, 25.27% id in 542 aa. Lies alongside a putative ABC transporter ATP-binding subunit.
  
     0.491
DIP1509
Putative secreted protein; Similar to the N-terminal region of Mycobacterium tuberculosis hypothetical 25.8 kDa protein Rv2891 precursor or MT2958.2 or MTCY274.22 SW:YS91_MYCTU (Q10812) (249 aa) fasta scores: E(): 2.1e-14, 39.05% id in 169 aa.
  
     0.450
DIP0991
Putative glycosyltransferase; Similar to Mycobacterium tuberculosis CDC1551 glycosyl transferase MT1250 TR:AAK45507 (EMBL:AE007001) (387 aa) fasta scores: E(): 2.9e-91, 60.72% id in 387 aa, and to Bacillus subtilis spore coat protein SA CotSA SW:CTSA_BACSU (P46915) (377 aa) fasta scores: E(): 1.6e-13, 24.37% id in 402 aa.
  
     0.417
DIP0993
Putative methyltransferase; Similar to Mycobacterium tuberculosis CDC1551 O-methyltransferase MT1258 TR:AAK45515 (EMBL:AE007002) (215 aa) fasta scores: E(): 6e-17, 37.91% id in 182 aa.
  
     0.413
DIP0553
Putative membrane protein; Low similarity to Streptomyces coelicolor putative membrane protein SCl2.30c TR:Q9L269 (EMBL:AL137778) (150 aa) fasta scores: E(): 1.9e-06, 35.48% id in 93 aa.
  
     0.402
DIP0019
Hypothetical protein; Doubtful CDS. No strong consensus RBS usptream. No significant database matches.
  
 
   0.400
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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