STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0543Putative sialidase precursor; Similar to Micromonospora viridifaciens sialidase precursor NedA SW:NANH_MICVI (Q02834) (647 aa) fasta scores: E(): 4e-06, 33.62% id in 455 aa. Note: Contains a potential colied-coil region at residues 518..639. (721 aa)    
Predicted Functional Partners:
DIP0330
Conserved hypothetical protein; C-terminal region similar to Micromonospora viridifaciens sialidase precursor NedA SW:NANH_MICVI (Q02834) (647 aa) fasta scores: E(): 1.8e-23, 34.24% id in 403 aa.
  
  
 
0.929
DIP0511
Conserved hypothetical protein (pseudogene; 1 probable transmembrane helix predicted for DIP0508 by TMHMM2.0; Belongs to the DapA family.
 
   
 0.653
DIP0544
Putative secreted protein; Similar to Streptomyces coelicolor putative secreted protein 3SC5B7.14c TR:Q9EWT5 (EMBL:AL449216) (231 aa) fasta scores: E(): 9.9e-08, 30.99% id in 242 aa.
       0.584
DIP0513
Putative oligopeptide transport system (integral membrane and ATP-binding proteins); C-terminal region similar to Salmonella typhimurium oligopeptide transport ATP-binding protein OppD or STM1743 SW:OPPD_SALTY (P04285) (335 aa) fasta scores: E(): 3.2e-38, 42.07% id in 328 aa, and N-terminal region to Bacillus firmus dipeptide transport system permease protein DppC SW:DPPC_BACFI (P94312) (304 aa) fasta scores: E(): 4.2e-32, 41.19% id in 267 aa.
 
     0.508
DIP0517
Putative GntR family regulatory protein; Similar to Escherichia coli galactonate operon transcriptional repressor DgoR or B3694/B3695 SW:DGOR_ECOLI (P31460) (229 aa) fasta scores: E(): 8.4e-09, 23.11% id in 199 aa.
 
     0.489
DIP0515
Similar to Escherichia coli O157:H7 EDL933 putative transport protein Z1054 TR:AAG55204 (EMBL:AE005264) (512 aa) fasta scores: E(): 4.3e-19, 24% id in 479 aa. Note: Contains a putative twin-arginine translocation (TAT) system recognition motif (RRDFFK) at the N-terminal region.
 
     0.467
secY
Preprotein translocase SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
     
 0.444
DIP0331
Conserved hypothetical protein; Similar to Klebsiella oxytoca YiaX1 TR:AAK69523 (EMBL:AF282849) (315 aa) fasta scores: E(): 4.4e-18, 31.94% id in 313 aa.
 
     0.434
DIP0443
Putative surface-anchored membrane protein; No significant database matches. Note: Contains a potential sortase anchor site (LPDTG) upstream of the C-terminal region transmembrane domain. Also similar to DIP0439, DIP1724, DIP0442 and DIP2325.
  
     0.419
DIP0439
Putative membrane protein; No significant database matches. Note: Also presents similarities with DIP1724, DIP0442, DIP2325 and DIP0443.
  
     0.406
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.