Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
DIP0552Conserved hypothetical protein; Low similarity to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3556 TR:AAK47896 (EMBL:AE007159) (482 aa) fasta scores: E(): 8.1e-16, 29.36% id in 487 aa. (432 aa)    
Predicted Functional Partners:
esxA
Similar to Mycobacterium tuberculosis hypothetical 11.1 kDa protein Rv3444c or MTCY77.16c TR:O06261 (EMBL:Z95389) (100 aa) fasta scores: E(): 1e-08, 35.48% id in 93 aa; Belongs to the WXG100 family. ESAT-6 subfamily.
 
 
 0.919
esxB
Very low similarity to Mycobacterium tuberculosis hypothetical 13.5 kDa protein Rv3445c or MTCY77.17c TR:O06262 (EMBL:Z95389) (125 aa) fasta scores: E(): 0.0007, 31.52% id in 92 aa; Belongs to the WXG100 family. CFP-10 subfamily.
 
 
 0.901
DIP0556
Similar to Mycobacterium tuberculosis CDC1551 FtsK/SpoIIIE family protein MT3553 TR:AAK47893 (EMBL:AE007159) (1200 aa) fasta scores: E(): 1.7e-97, 37.59% id in 1221 aa.
 
 
 0.850
DIP2191
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 35.4 kDa protein Rv3802c or MTV026.07c TR:O53581 (EMBL:AL022076) (336 aa) fasta scores: E(): 3.2e-34, 41.32% id in 317 aa.
  
 
 0.793
DIP0793
Putative secreted protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2601 TR:AAK46909 (EMBL:AE007096) (240 aa) fasta scores: E(): 4.3e-31, 46.31% id in 244 aa. Note: Contains a putative twin-arginine translocation (TAT) system recognition motif (RRSFLT) at the N-terminal region.
  
   
 0.778
DIP0555
Putative surface-anchored membrane protein; Very low similarity to Mycobacterium tuberculosis hypothetical protein Rv3448 or MTCY77.20 or MT3554 SWALL:O33354 (EMBL:Z95390) (467 aa) fasta scores: E(): 0.0016, 21.96% id in 478 aa. Note: Contains a putative sortase anchor site (LPNTG).
 
 
 
 0.756
DIP1556
Putative membrane protein; Low similarity to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT1645 TR:AAK45914 (EMBL:AE007029) (235 aa) fasta scores: E(): 1e-08, 28.64% id in 206 aa.
  
     0.750
DIP2098
Putative secreted protein; No significant database matches.
  
     0.749
DIP1097
Similar to Mycobacterium tuberculosis low molecular weight protein antigen 6 Cfp6 or Rv3004 or MT3084.1 or MTV012.18 SW:CFP6_MYCTU (O53251) (112 aa) fasta scores: E(): 7.9e-07, 34.57% id in 107 aa.
  
     0.746
DIP0865
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 39.5 kDa protein Rv0996 or MTCI237.10 TR:O05579 (EMBL:Z94752) (358 aa) fasta scores: E(): 1.8e-13, 30.27% id in 370 aa.
  
     0.729
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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