Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
esxASimilar to Mycobacterium tuberculosis hypothetical 11.1 kDa protein Rv3444c or MTCY77.16c TR:O06261 (EMBL:Z95389) (100 aa) fasta scores: E(): 1e-08, 35.48% id in 93 aa; Belongs to the WXG100 family. ESAT-6 subfamily. (95 aa)    
Predicted Functional Partners:
esxB
Very low similarity to Mycobacterium tuberculosis hypothetical 13.5 kDa protein Rv3445c or MTCY77.17c TR:O06262 (EMBL:Z95389) (125 aa) fasta scores: E(): 0.0007, 31.52% id in 92 aa; Belongs to the WXG100 family. CFP-10 subfamily.
 
 
 0.999
DIP0556
Similar to Mycobacterium tuberculosis CDC1551 FtsK/SpoIIIE family protein MT3553 TR:AAK47893 (EMBL:AE007159) (1200 aa) fasta scores: E(): 1.7e-97, 37.59% id in 1221 aa.
 
 
 
 0.951
DIP0552
Conserved hypothetical protein; Low similarity to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3556 TR:AAK47896 (EMBL:AE007159) (482 aa) fasta scores: E(): 8.1e-16, 29.36% id in 487 aa.
 
 
 0.919
DIP1461
Putative cell division protein; Similar to Streptomyces coelicolor FtsK homolog SC7C7.05 TR:O86810 (EMBL:AL031031) (929 aa) fasta scores: E(): 2.1e-106, 50.17% id in 837 aa, and similar to C-terminal region of Escherichia coli cell division protein FtsK or B0890 SW:FTSK_ECOLI (P46889) (1329 aa) fasta scores: E(): 6.5e-34, 39.14% id in 700 aa.
   
 
 0.782
DIP0555
Putative surface-anchored membrane protein; Very low similarity to Mycobacterium tuberculosis hypothetical protein Rv3448 or MTCY77.20 or MT3554 SWALL:O33354 (EMBL:Z95390) (467 aa) fasta scores: E(): 0.0016, 21.96% id in 478 aa. Note: Contains a putative sortase anchor site (LPNTG).
 
   
 0.781
DIP0560
Hypothetical protein; Doubtful CDS. No strong consensus RBS usptream. No significant database matches.
       0.741
DIP0716
Putative secreted protein; Low similarity to Mycobacterium leprae putative membrane protein ML0810 TR:Q9CCH4 (EMBL:AL583919) (407 aa) fasta scores: E(): 1.1e-21, 26.81% id in 414 aa.
  
     0.687
DIP0639
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 45.7 kDa protein Rv3311 or MTV016.10 TR:O53362 (EMBL:AL021841) (420 aa) fasta scores: E(): 1.4e-25, 34.05% id in 417 aa.
  
     0.676
DIP1132
Putative exported protein; Similar to Mycobacterium leprae possible secreted protein ML1677 TR:Q9CBS1 (EMBL:AL583923) (191 aa) fasta scores: E(): 8.9e-13, 32.447% id in 188 aa, and to Mycobacterium tuberculosis hypothetical 18.8 kDa protein Rv2980 or MTCY349.07c TR:P95115 (EMBL:Z83018) (181 aa) fasta scores: E(): 1.5e-09, 31.098% id in 164 aa.
  
     0.663
DIP0554
Putative subtilisin-like cell wall associated serine protease (mycosin); Similar to Streptomyces coelicolor serine protease SC3C3.08 TR:O86642 (EMBL:AL031231) (413 aa) fasta scores: E(): 4e-11, 32.37% id in 278 aa and to Mycobacterium tuberculosis hypothetical 46.0 kDa protein Rv3449 or MTCY13E12.02 or MT3555 SWALL:O06316 (EMBL:Z95390) (455 aa) fasta scores: E(): 4.7e-10, 38.11% id in 307 aa.
  
  
 0.621
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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