STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0572Conserved hypothetical protein; Similar to Mycobacterium leprae hypothetical 38.0 kDa protein ML0378 precursor or B229_C1_170 SW:YY21_MYCLE (Q49857) (359 aa) fasta scores: E(): 4.2e-30, 48.16% id in 218 aa. (222 aa)    
Predicted Functional Partners:
tsaD
Putative endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
  
 
 0.995
DIP0569
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 18.2 kDa protein Rv3422c or MT3531 or MTCY78.07 SW:YY22_MYCTU (Q50706) (168 aa) fasta scores: E(): 4.4e-19, 46.71% id in 152 aa.
  
 
 0.975
DIP0573
Similar to Escherichia coli ribosomal-protein-alanine acetyltransferase RimI or B4373 or Z5974 or ECS5331 SW:RIMI_ECOLI (P09453) (148 aa) fasta scores: E(): 4.9e-09, 34.4% id in 125 aa.
 
 
 0.973
groES
10 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
     
 0.730
DIP0571
Putative secreted protein; No significant database matches.
       0.717
groEL1
60 kDa chaperonin 1; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
     
 0.652
murC
UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
  
 0.620
DIP0688
Conserved hypothetical protein; Similar in its N-terminal region to Mycobacterium tuberculosis hypothetical 35.3 kDa protein Rv3256c or MTV015.01c or MTCY20b11.31c TR:O05899 (EMBL:Z95121) (346 aa) fasta scores: E(): 5.1e-06, 27.69% id in 260 aa.
      
 0.602
cobN
Putative cobalamin biosynthesis related protein; Similar to Mycobacterium tuberculosis CobN or Rv2062c or MT2121 or MTCY49.01c or MTV019.03 SWALL:AAK46401 (EMBL:AL021922) (1195 aa) fasta scores: E(): 0, 62.22% id in 1215 aa, and to Methanococcus jannaschii hypothetical protein MJ0908 SWALL:Q58318 (EMBL:U67534) (1232 aa) fasta scores: E(): 5.1e-109, 36.48% id in 1258 aa.
      
 0.602
DIP0568
Putative alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
     
 0.539
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.