Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DIP0572Conserved hypothetical protein; Similar to Mycobacterium leprae hypothetical 38.0 kDa protein ML0378 precursor or B229_C1_170 SW:YY21_MYCLE (Q49857) (359 aa) fasta scores: E(): 4.2e-30, 48.16% id in 218 aa. (222 aa)    
Predicted Functional Partners:
tsaD
Putative endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
  
 
 0.990
DIP0569
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 18.2 kDa protein Rv3422c or MT3531 or MTCY78.07 SW:YY22_MYCTU (Q50706) (168 aa) fasta scores: E(): 4.4e-19, 46.71% id in 152 aa.
  
 
 0.981
DIP0573
Similar to Escherichia coli ribosomal-protein-alanine acetyltransferase RimI or B4373 or Z5974 or ECS5331 SW:RIMI_ECOLI (P09453) (148 aa) fasta scores: E(): 4.9e-09, 34.4% id in 125 aa.
 
 
 0.967
DIP0571
Putative secreted protein; No significant database matches.
       0.703
groES
10 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
     
 0.670
groEL1
60 kDa chaperonin 1; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
     
 0.635
murC
UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
  
 0.524
DIP0661
Putative biotin synthesis-related regulatory protein; Similar to C-terminal region of Escherichia coli BirA bifunctional protein BirA or BioR or DhbB or B3973 SW:BIRA_ECOLI (P06709) (321 aa) fasta scores: E(): 2e-15, 32.12% id in 221 aa.
  
    0.507
DIP0568
Putative alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
     
 0.503
DIP0688
Conserved hypothetical protein; Similar in its N-terminal region to Mycobacterium tuberculosis hypothetical 35.3 kDa protein Rv3256c or MTV015.01c or MTCY20b11.31c TR:O05899 (EMBL:Z95121) (346 aa) fasta scores: E(): 5.1e-06, 27.69% id in 260 aa.
      
 0.496
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.