STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tsaDPutative endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (350 aa)    
Predicted Functional Partners:
DIP0572
Conserved hypothetical protein; Similar to Mycobacterium leprae hypothetical 38.0 kDa protein ML0378 precursor or B229_C1_170 SW:YY21_MYCLE (Q49857) (359 aa) fasta scores: E(): 4.2e-30, 48.16% id in 218 aa.
  
 
 0.995
DIP0538
Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 46.2 kDa protein SC5F8.10c TR:Q9K4L4 (EMBL:AL357613) (410 aa) fasta scores: E(): 2.1e-74, 50% id in 394 aa.
  
 0.980
DIP0569
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 18.2 kDa protein Rv3422c or MT3531 or MTCY78.07 SW:YY22_MYCTU (Q50706) (168 aa) fasta scores: E(): 4.4e-19, 46.71% id in 152 aa.
 
 
 0.956
DIP0573
Similar to Escherichia coli ribosomal-protein-alanine acetyltransferase RimI or B4373 or Z5974 or ECS5331 SW:RIMI_ECOLI (P09453) (148 aa) fasta scores: E(): 4.9e-09, 34.4% id in 125 aa.
  
  
 0.893
pheT
Similar to Mycobacterium tuberculosis phenylalanyl-tRNA synthetase beta chain PheT or Rv1650 or MT1688 or MTCY06H11.15 SWALL:SYFB_MYCTU (SWALL:P94985) (831 aa) fasta scores: E(): 4.2e-156, 49.64% id in 844 aa, and to Bacillus subtilis phenylalanyl-tRNA synthetase beta chain PheT SWALL:SYFB_BACSU (SWALL:P17922) (804 aa) fasta scores: E(): 1.8e-53, 30.69% id in 847 aa.
 
  
 0.724
DIP0571
Putative secreted protein; No significant database matches.
       0.717
pheS
Similar to Mycobacterium tuberculosis phenylalanyl-tRNA synthetase alpha chain PheS or Rv1649 or MT1687 or MTCY06H11.14 SWALL:SYFA_MYCTU (SWALL:P94984) (341 aa) fasta scores: E(): 6.6e-87, 62.35% id in 340 aa, and to Bacillus subtilis phenylalanyl-tRNA synthetase alpha chain PheS SWALL:SYFA_BACSU (SWALL:P17921) (344 aa) fasta scores: E(): 2.6e-54, 44.02% id in 343 aa, and to Escherichia coli phenylalanyl-tRNA synthetase alpha chain PheS or B1714 SWALL:SYFA_ECOLI (SWALL:P08312) (327 aa) fasta scores: E(): 7.1e-52, 44.71% id in 331 aa; Belongs to the class-II aminoacyl-tRNA synthetase fa [...]
 
   
 0.695
groES
10 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
     
 0.689
ychF
Putative ABC transport system ATP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
 
  
 0.677
groEL1
60 kDa chaperonin 1; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
     
 0.661
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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