STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0579Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 15.3 kDa protein Rv3412 or MT3521 or MTCY78.16C SW:YY12_MYCTU (Q50714) (136 aa) fasta scores: E(): 7.8e-18, 43.36% id in 113 aa. (128 aa)    
Predicted Functional Partners:
DIP0702
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 17.8 kDa protein Rv3231c or MTCY20B11.06c TR:O05876 (EMBL:Z95121) (169 aa) fasta scores: E(): 2.4e-25, 53.52% id in 170 aa.
  
     0.760
DIP1610
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 22.9 kDa protein Rv2170 or MTV021.03 TR:O53504 (EMBL:AL021957) (206 aa) fasta scores: E(): 3.4e-16, 35.14% id in 202 aa.
  
     0.742
secE
Putative translocase protein; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
  
     0.729
DIP1617
Conserved hypothetical protein; Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
  
     0.715
DIP1184
Putative secreted protein; Similar to Mycobacterium tuberculosis hypothetical 32.4 kDa protein Rv1698 precursor or MT1737 or MTCI125.20 SWALL:YG98_MYCTU (SWALL:P58212) (314 aa) fasta scores: E(): 4.4e-22, 31.57% id in 304 aa.
  
     0.713
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
       0.682
DIP0315
Putative secreted protein; Similar to Mycobacterium tuberculosis hypothetical 19.1 kDa protein Rv3657c or MTV025.005c TR:O69625 (EMBL:AL022121) (191 aa) fasta scores: E(): 2.9e-10, 36.66% id in 150 aa.
  
     0.670
DIP2110
Putative oxidoreductase; Similar to Mycobacterium bovis 47 kDa protein Rv0385 or MT0398 or MTV036.20 TR:O86363 (EMBL:U73653) (390 aa) fasta scores: E(): 4.7e-29, 36.36% id in 352 aa, and to Acinetobacter calcoaceticus phenolhydroxylase component TR:Q43983 (EMBL:Z36909) (350 aa) fasta scores: E(): 2.2e-06, 25.61% id in 246 aa, and to Pseudomonas sp phenol hydroxylase P5 protein DmpP SW:DMPP_PSESP (P19734) (352 aa) fasta scores: E(): 8.3e-06, 24.3% id in 251 aa.
  
     0.660
DIP2282
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis 35 kDa protein Rv2744c or MT2815 or MTV002.09c SWALL:35KD_MYCTU (SWALL:P31511) (270 aa) fasta scores: E(): 8.4e-29, 45.52% id in 257 aa.
  
     0.658
DIP1455
Conserved hypothetical protein; Similar in its full length to Mycobacterium tuberculosis 35 kDa protein Rv2744c or MT2815 or MTV002.09c SW:35KD_MYCTU (P31511) (270 aa) fasta scores: E(): 1.2e-51, 75.8% id in 248 aa, N-terminal region to Mycobacterium leprae B2235_C2_187 MLCB33.06c TR:Q49840 (EMBL:U00019) (167 aa) fasta scores: E(): 2.9e-27, 72.1% id in 147 aa, and C-terminal region to Mycobacterium leprae B2235_C3_214 MLCB33.05c TR:Q49845 (EMBL:U00019) (114 aa) fasta scores: E(): 3.4e-12, 58.18% id in 110 aa.
  
     0.638
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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