STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0585Similar to Bacillus subtilis ferrichrome transport ATP-binding protein FhuC SW:FHUC_BACSU (P49938) (269 aa) fasta scores: E(): 1.2e-37, 45.13% id in 257 aa, and to Escherichia coli iron FecE or B4287 SW:FECE_ECOLI (P15031) (255 aa) fasta scores: E(): 5e-32, 42.8% id in 250 aa. (270 aa)    
Predicted Functional Partners:
DIP0583
Putative iron transport system membrane protein; Similar to Escherichia coli iron FecC or B4289 SW:FECC_ECOLI (P15030) (332 aa) fasta scores: E(): 1.6e-22, 33.77% id in 305 aa; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.986
DIP0584
Putative iron transport system membrane protein; Similar to Escherichia coli iron FecD or B4288 SW:FECD_ECOLI (P15029) (318 aa) fasta scores: E(): 2.6e-28, 35.01% id in 317 aa; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.978
DIP0582
Putative iron transport system binding (secreted) protein; Similar to Escherichia coli iron FecB or B4290 SW:FECB_ECOLI (P15028) (300 aa) fasta scores: E(): 1.6e-12, 28.57% id in 287 aa.
 
  
 0.948
DIP0448
Similar to Streptomyces coelicolor putative ABC transport system ATP-binding protein SCE41.20c TR:Q9F2N9 (EMBL:AL442120) (262 aa) fasta scores: E(): 2.4e-29, 44.49% id in 236 aa.
 
   
0.920
DIP1061
Similar to Streptomyces coelicolor putative iron-siderophore uptake system transmembrane component sci51.27C TR:Q9S213 (EMBL:AL109848) (348 aa) fasta scores: E(): 8e-36, 36.53% id in 323 aa, and to Escherichia coli ferric enterobactin transport system permease protein fepD or B0590 SW:FEPD_ECOLI (P23876) (334 aa) fasta scores: E(): 5.2e-40, 40.37% id in 322 aa; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.917
DIP1062
Putative iron-siderophore uptake system exported solute-binding component; Similar to Escherichia coli iron(III) dicitrate-binding periplasmic protein precursor FecB or B4290 SW:FECB_ECOLI (P15028) (300 aa) fasta scores: E(): 1.1e-12, 25.55% id in 270 aa, and to Campylobacter jejuni enterochelin uptake periplasmic binding protein CeuE or CJ1355 TR:Q9PMU4 (EMBL:AL139078) (330 aa) fasta scores: E(): 3e-12, 28.35% id in 328 aa, and to Vibrio anguillarum ferric anguibactin-binding protein precursor FatB SW:FATB_VIBAN (P11460) (322 aa) fasta scores: E(): 1.5e-09, 28.72% id in 289 aa.
 
 
 0.880
hmuU
Iron-related transport system membrane protein; Almost identical to previously sequenced Corynebacterium diphtheriae HmuU TR:Q9XD88 (EMBL:AF109162) (350 aa) fasta scores: E(): 6.1e-120, 98% id in 350 aa, and highly similar to Corynebacterium ulcerans permease HmuU TR:Q9EZ56 (EMBL:AF304009) (350 aa) fasta scores: E(): 4.3e-100, 81.14% id in 350 aa; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
   0.856
DIP1084
Similar to Streptomyces coelicolor putative FecCD-family membrane transport protein SC2H12.15 TR:Q9K469 (EMBL:AL359215) (368 aa) fasta scores: E(): 2.3e-50, 48.1% id in 343 aa, and to Yersinia pestis hemin transport system permease protein HmuU YPO0280 SW:HMUU_YERPE (Q56992) (334 aa) fasta scores: E(): 6.8e-30, 36.33% id in 344 aa.
 
   0.855
irp6B
Membrane protein permease Irp6B; Almost identical to previously sequenced Corynebacterium diphtheriae membrane protein permease Irp6B SWALL:Q8VVA7 (EMBL:AY061890) (347 aa) fasta scores: E(): 1e-116, 98.27% id in 347 aa and similar to Rhizobium meliloti putative iron ABC transporter permease protein SMB21430 TR:CAC49658 (EMBL:AL603646) (356 aa) fasta scores: E(): 1.6e-55, 50.87% id in 342 aa and to Corynebacterium diphtheriae HmuU SWALL:Q9XD88 (EMBL:AF109162) (350 aa) fasta scores: E(): 2.1e-36, 40.66% id in 332 aa; Belongs to the binding-protein-dependent transport system permease fami [...]
 
   0.831
DIP1060
Similar to Streptomyces coelicolor putative iron-siderophore uptake system transmembrane component sci51.26C TR:Q9S214 (EMBL:AL109848) (375 aa) fasta scores: E(): 5e-40, 40.74% id in 324 aa, and to Escherichia coli ferric enterobactin transport system permease protein fepg fepg or B0589 SW:FEPG_ECOLI (P23877) (330 aa) fasta scores: E(): 1.8e-45, 44.09% id in 322 aa; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
  
 0.826
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.