Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DIP0586Putative siderophore biosynthesis related protein; Similar in its N-terminal region and C-terminal region to Rhizobium sp hypothetical 71.0 kDa protein Y4xN SW:Y4XN_RHISN (P55706) blast scores: E(): 3e-23, score: 277 22% id and also to Rhizobium meliloti rhizobactin siderophore biosynthesis protein RhbC or RhsC or RA1260 or SMA2404 SWALL:AAK65918 (EMBL:AF110737) (585 aa) fasta scores: E(): 6e-12, 26.23% id in 526 aa. Possible duplication. (1107 aa)    
Predicted Functional Partners:
DIP0582
Putative iron transport system binding (secreted) protein; Similar to Escherichia coli iron FecB or B4290 SW:FECB_ECOLI (P15028) (300 aa) fasta scores: E(): 1.6e-12, 28.57% id in 287 aa.
 
  
 0.753
DIP0585
Similar to Bacillus subtilis ferrichrome transport ATP-binding protein FhuC SW:FHUC_BACSU (P49938) (269 aa) fasta scores: E(): 1.2e-37, 45.13% id in 257 aa, and to Escherichia coli iron FecE or B4287 SW:FECE_ECOLI (P15031) (255 aa) fasta scores: E(): 5e-32, 42.8% id in 250 aa.
  
  
 0.724
DIP0583
Putative iron transport system membrane protein; Similar to Escherichia coli iron FecC or B4289 SW:FECC_ECOLI (P15030) (332 aa) fasta scores: E(): 1.6e-22, 33.77% id in 305 aa; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
     
 0.722
DIP0584
Putative iron transport system membrane protein; Similar to Escherichia coli iron FecD or B4288 SW:FECD_ECOLI (P15029) (318 aa) fasta scores: E(): 2.6e-28, 35.01% id in 317 aa; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
     
 0.712
DIP0587
Putative membrane protein; Similar to Streptomyces coelicolor putative membrane transport protein SC5F8.19 TR:Q9K4K5 (EMBL:AL357613) (444 aa) fasta scores: E(): 7.2e-10, 27.72% id in 404 aa.
     
 0.654
DIP2161
Nonribosomal peptide synthase; Similar to Stigmatella aurantiaca myxothiazol synthase MtaC TR:Q9RFK9 (EMBL:AF188287) (1290 aa) fasta scores: E(): 1.7e-86, 35.694% id in 1073 aa, and to Polyangium cellulosum epothilone biosynthase EpoB TR:Q9KIZ9 (EMBL:AF217189) (1410 aa) fasta scores: E(): 1.8e-81, 35.385% id in 975 aa, and to Pseudomonas aeruginosa pyochelin synthetase PchF or PA4225 TR:Q9HWG4 (EMBL:AE004839) (1809 aa) fasta scores: E(): 1.9e-81, 37.017% id in 932 aa.
 
  
 0.621
DIP0588
Putative membrane protein; No significant database matches.
       0.573
DIP2272
Possible sortase-like protein; Similar to Clostridium acetobutylicum sortase CAC0204 TR:AAK78186 (EMBL:AE007533) (194 aa) fasta scores: E(): 2.6e-06, 30.872% id in 149 aa, and weakly similar to Actinomyces naeslundii putative fimbria-associated protein TR:O68213 (EMBL:AF019629) (365 aa) fasta scores: E(): 0.25, 32.941% id in 85 aa, and to Streptococcus pneumoniae TIGR4 sortase, putative SP0466 TR:AAK74626 (EMBL:AE007358) (279 aa) fasta scores: E(): 5.3, 25.000% id in 144 aa.
      
 0.560
DIP2304
Similar to Streptomyces coelicolor putative DNA repair hydrolase SCC80.11c SWALL:Q9F308 (EMBL:AL442143) (306 aa) fasta scores: E(): 1.1e-52, 53.22% id in 295 aa, and to Escherichia coli formamidopyrimidine-DNA glycosylase MutM or Fpg or B3635 SWALL:FPG_ECOLI (SWALL:P05523) (269 aa) fasta scores: E(): 1.2e-12, 29.21% id in 243 aa; Belongs to the FPG family.
      
 0.541
DIP2165
Similar to Rhizobium meliloti putative ABC transporter SMA0298 TR:AAK64817 (EMBL:AE007209) (604 aa) fasta scores: E(): 1.5e-15, 27.536% id in 552 aa, and to Streptomyces coelicolor putative peptide transport ATP-binding protein SC9F2.04 TR:Q9Z531 (EMBL:AL035559) (359 aa) fasta scores: E(): 3.4e-15, 39.409% id in 203 aa.
      
 0.446
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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