STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0599Similar to Streptomyces coelicolor putative two-component system sensor kinase SCD63A.02 TR:Q9KY73 (EMBL:AL356832) (430 aa) fasta scores: E(): 3e-12, 37.09% id in 434 aa. (403 aa)    
Predicted Functional Partners:
DIP0600
Similar to Streptomyces coelicolor putative two-component system DNA-binding response regulator SSCD63A.03 TR:Q9KY72 (EMBL:AL356832) (251 aa) fasta scores: E(): 3.8e-26, 58.72% id in 235 aa, and to Bacillus brevis transcriptional regulatory protein DegU SW:DEGU_BACBR (P54662) (236 aa) fasta scores: E(): 2.7e-10, 30.97% id in 226 aa.
 
 
 0.948
DIP1455
Conserved hypothetical protein; Similar in its full length to Mycobacterium tuberculosis 35 kDa protein Rv2744c or MT2815 or MTV002.09c SW:35KD_MYCTU (P31511) (270 aa) fasta scores: E(): 1.2e-51, 75.8% id in 248 aa, N-terminal region to Mycobacterium leprae B2235_C2_187 MLCB33.06c TR:Q49840 (EMBL:U00019) (167 aa) fasta scores: E(): 2.9e-27, 72.1% id in 147 aa, and C-terminal region to Mycobacterium leprae B2235_C3_214 MLCB33.05c TR:Q49845 (EMBL:U00019) (114 aa) fasta scores: E(): 3.4e-12, 58.18% id in 110 aa.
  
 
 0.875
DIP2282
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis 35 kDa protein Rv2744c or MT2815 or MTV002.09c SWALL:35KD_MYCTU (SWALL:P31511) (270 aa) fasta scores: E(): 8.4e-29, 45.52% id in 257 aa.
  
 
 0.875
DIP0598
Putative membrane protein; No significant database matches.
 
    0.821
DIP1889
Similar to Streptomyces coelicolor putative transcriptional regulator SC2G5.15C TR:Q9Z5A8 (EMBL:AL035478) (279 aa) fasta scores: E(): 9.5e-35, 44.89% id in 274 aa, and to Rhizobium meliloti putative transcription regulator protein SMC03015 TR:CAC45219 (EMBL:AL591784) (245 aa) fasta scores: E(): 0.012, 25.55% id in 227 aa.
 
 
 0.561
DIP0063
Putative two-component system sensor protein; Similar to Escherichia coli sensor protein BaeS or B2078 SW:BAES_ECOLI (P30847) (467 aa) fasta scores: E(): 1.8e-28, 33.333% id in 372 aa.
   
 
 0.529
mtrB
Putative two component system sensor kinase; Similar to Mycobacterium tuberculosis MtrB or Rv3245c or MTCY20B11.20c TR:O05890 (EMBL:Z95121) (567 aa) fasta scores: E(): 4.6e-89, 53.73% id in 482 aa, and to Streptomyces coelicolor sensor protein AfsQ2 or 2SCK8.32c SW:AFQ2_STRCO (Q04943) (535 aa) fasta scores: E(): 1.4e-23, 30.64% id in 447 aa.
   
 
 0.529
DIP1935
Putative two somponent system sensor kinase protein; C-terminal region is similar to Mycobacterium tuberculosis hypothetical protein Rv0758 TR:P71815 (EMBL:Z80226) (485 aa) fasta scores: E(): 7.7e-38, 42.88% id in 471 aa, and to Bacillus halodurans two-component sensor histidine kinase BH0373 TR:Q9KFU8 (EMBL:AP001508) (459 aa) fasta scores: E(): 3.7e-29, 30.81% id in 464 aa.
   
 
 0.529
DIP0091
Putative two-component system response regulator; Similar to Streptomyces lividans response regulator homolog TR:P72471 (EMBL:U63847) (225 aa) fasta scores: E(): 2.7e-29, 42.98% id in 221 aa, and to Streptomyces coelicolor putative two-component system regulator SCH10.18c TR:Q9X8Q7 (EMBL:AL049754) (228 aa) fasta scores: E(): 3e-26, 38.53% id in 218 aa.
  
 
 0.500
cstA
Response regulator; Identical to previously sequenced Corynebacterium diphtheriae response regulator CstA TR:Q9RPE7 (EMBL:AF161328) (233 aa) fasta scores: E(): 4.9e-83, 99.57% id in 233 aa.
  
 
 0.500
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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