STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metNPutative ABC transport system ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (340 aa)    
Predicted Functional Partners:
DIP0608
Putative ABC transport system membrane protein; Similar to Staphylococcus aureus (strain N315) SA0421 protein or SAV0463 TR:BAB56625 (EMBL:AP003130) (219 aa) fasta scores: E(): 1.7e-31, 46.6% id in 206 aa, and to Salmonella enteritidis integral membrane protein SfbC TR:Q9S4Y9 (EMBL:AF102556) (202 aa) fasta scores: E(): 8.9e-28, 42.71% id in 199 aa.
 
 0.999
DIP0610
Putative ABC transport system secreted protein; Similar to Escherichia coli lipoprotein-28 precursor NlpA or B3661 SW:NLPA_ECOLI (P04846) (272 aa) fasta scores: E(): 1.9e-20, 34.36% id in 259 aa. Possible duplication of the CDS upstream, CDIP0611 (66.667% identity in 288 aa overlap).
 
 0.999
DIP0611
Putative ABC transport system secreted protein; Similar to Escherichia coli lipoprotein-28 precursor NlpA or B3661 SW:NLPA_ECOLI (P04846) (272 aa) fasta scores: E(): 1.5e-20, 33.83% id in 266 aa. Possible duplication of the CDS downstream, CDIP0610 (66.667% identity in 288 aa overlap).
 
 0.999
DIP0014
Putative membrane protein; Low similarity to Staphylococcus aureus subsp aureus N315 SA0639 protein TR:Q99VT7 (EMBL:AP003131) (543 aa) fasta scores: E(): 3e-23, 25.56% id in 485 aa.
 
     
0.851
DIP0485
Putative ABC transport system integral membrane protein; Similar to Bacillus halodurans BH3121 protein TR:Q9K885 (EMBL:AP001517) (398 aa) fasta scores: E(): 4e-20, 33.33% id in 438 aa.
 
     0.775
DIP0015
Putative transport system, ATP-binding protein; Similar to Escherichia coli, and Escherichia coli O157:H7 probable transport ATP-binding protein MsbA or B0914 or Z1260 or ECS0997 SWALL:MSBA_ECOLI (SWALL:P27299) (582 aa) fasta scores: E(): 7e-30, 26.73% id in 561 aa, and to Pasteurella multocida hypothetical protein PM1473 TR:Q9CKX8 (EMBL:AE006183) (552 aa) fasta scores: E(): 6.1e-33, 27.97% id in 554 aa.
 
     
0.744
DIP0619
Putative diphtheria toxin repressor 2; Similar to Mycobacterium tuberculosis iron-dependent repressor IdeR or DtxR or Rv2711 or MT2784 or MTCY05A6.32 SW:IDER_MYCTU (Q50495) (230 aa) fasta scores: E(): 1.1e-10, 31.84% id in 201 aa and low similarity to Corynebacterium diphtheriae diphtheria toxin repressor DtxR SW:DTXR_CORDI (P33120) (226 aa) fasta scores: E(): 7.7e-08, 35.08% identity in 114 aa overlap.
   
   0.604
DIP1611
Similar to Streptomyces lividans 5,10-methylenetetrahydrofolate reductase MetF SW:METF_STRLI (O54235) (307 aa) fasta scores: E(): 4.1e-41, 41.58% id in 303 aa, and to Escherichia coli 5,10-methylenetetrahydrofolate reductase MetF or B3941 SW:METF_ECOLI (P00394) (296 aa) fasta scores: E(): 9.2e-15, 33.65% id in 309 aa.
   
  
 0.549
DIP0909
Putative ABC transport system ATP-binding protein; Similar to C-terminal region of Mycobacterium smegmatis ExiT TR:O85018 (EMBL:AF034152) (1122 aa) fasta scores: E(): 5.9e-45, 34.56% id in 596 aa, and to Streptomyces coelicolor putative ABC-transporter transmembrane protein SCF34.12c TR:Q9RK13 (EMBL:AL109974) (601 aa) fasta scores: E(): 1.5e-42, 33.98% id in 612 aa.
 
    
0.546
DIP0607
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 33.4 kDa protein Rv3104c or MTCY164.14c TR:O05781 (EMBL:Z95150) (308 aa) fasta scores: E(): 1.3e-15, 33.94% id in 271 aa.
       0.527
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.