Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DIP0630 | ilvA | DIP0630 | DIP1579 | Putative methionine biosynthesis-related protein; Similar to Mycobacterium tuberculosis CDC1551 transulfuration enzyme family protein MT3443 TR:AAK47787 (EMBL:AE007151) (449 aa) fasta scores: E(): 4.8e-93, 56.94% id in 432 aa, and to Pseudomonas aeruginosa O-succinylhomoserine sulfhydrylase MetZ or PA3107 SW:METZ_PSEAE (P55218) (403 aa) fasta scores: E(): 2.7e-26, 39.31% id in 435 aa. | Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.807 |
| DIP0630 | metX | DIP0630 | DIP0623 | Putative methionine biosynthesis-related protein; Similar to Mycobacterium tuberculosis CDC1551 transulfuration enzyme family protein MT3443 TR:AAK47787 (EMBL:AE007151) (449 aa) fasta scores: E(): 4.8e-93, 56.94% id in 432 aa, and to Pseudomonas aeruginosa O-succinylhomoserine sulfhydrylase MetZ or PA3107 SW:METZ_PSEAE (P55218) (403 aa) fasta scores: E(): 2.7e-26, 39.31% id in 435 aa. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.996 |
| DIP0630 | thrA | DIP0630 | DIP1036 | Putative methionine biosynthesis-related protein; Similar to Mycobacterium tuberculosis CDC1551 transulfuration enzyme family protein MT3443 TR:AAK47787 (EMBL:AE007151) (449 aa) fasta scores: E(): 4.8e-93, 56.94% id in 432 aa, and to Pseudomonas aeruginosa O-succinylhomoserine sulfhydrylase MetZ or PA3107 SW:METZ_PSEAE (P55218) (403 aa) fasta scores: E(): 2.7e-26, 39.31% id in 435 aa. | Similar to Corynebacterium glutamicum homoserine dehydrogenase Hom or ThrA SW:DHOM_CORGL (P08499) (445 aa) fasta scores: E(): 4.2e-117, 75.28% id in 437 aa, and to Bacillus subtilis homoserine dehydrogenase Hom or Tdm SW:DHOM_BACSU (P19582) (433 aa) fasta scores: E(): 4.2e-54, 40.18% id in 433 aa. | 0.846 |
| DIP1199 | metX | DIP1199 | DIP0623 | Putative methyltransferase; Similar to, although longer in its N-terminal region than Mycobacterium tuberculosis putative methyltransferase Rv3342 or MT3445 or MTV016.42 SWALL:YX42_MYCTU (SWALL:O53392) (243 aa) fasta scores: E(): 2e-16, 31.71% id in 227 aa, and to Pseudomonas aeruginosa hypothetical protein PA0558 SWALL:Q9I5X8 (EMBL:AE004492) (255 aa) fasta scores: E(): 8.9e-11, 28.06% id in 253 aa. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.801 |
| DIP1863 | glyA | DIP1863 | DIP0932 | Putative hydrolase; Similar to Mycobacterium tuberculosis hypothetical protein Rv3042c TR:AAK47457 (EMBL:AL021287) (409 aa) fasta scores: E(): 3.1e-69, 54.54% id in 407 aa, and to Mycobacterium leprae putative phosphoserine phosphatase ML1727 TR:Q9CBQ6 (EMBL:AL583923) (411 aa) fasta scores: E(): 6.2e-66, 53.82% id in 405 aa. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.938 |
| DIP1863 | ilvA | DIP1863 | DIP1579 | Putative hydrolase; Similar to Mycobacterium tuberculosis hypothetical protein Rv3042c TR:AAK47457 (EMBL:AL021287) (409 aa) fasta scores: E(): 3.1e-69, 54.54% id in 407 aa, and to Mycobacterium leprae putative phosphoserine phosphatase ML1727 TR:Q9CBQ6 (EMBL:AL583923) (411 aa) fasta scores: E(): 6.2e-66, 53.82% id in 405 aa. | Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.908 |
| DIP1863 | metX | DIP1863 | DIP0623 | Putative hydrolase; Similar to Mycobacterium tuberculosis hypothetical protein Rv3042c TR:AAK47457 (EMBL:AL021287) (409 aa) fasta scores: E(): 3.1e-69, 54.54% id in 407 aa, and to Mycobacterium leprae putative phosphoserine phosphatase ML1727 TR:Q9CBQ6 (EMBL:AL583923) (411 aa) fasta scores: E(): 6.2e-66, 53.82% id in 405 aa. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.800 |
| DIP1863 | sdaA | DIP1863 | DIP0490 | Putative hydrolase; Similar to Mycobacterium tuberculosis hypothetical protein Rv3042c TR:AAK47457 (EMBL:AL021287) (409 aa) fasta scores: E(): 3.1e-69, 54.54% id in 407 aa, and to Mycobacterium leprae putative phosphoserine phosphatase ML1727 TR:Q9CBQ6 (EMBL:AL583923) (411 aa) fasta scores: E(): 6.2e-66, 53.82% id in 405 aa. | L-serine dehydratase 1; Similar to Escherichia coli L-serine dehydratase 1 SdaA or B1814 SW:SDHL_ECOLI (P16095) (454 aa) fasta scores: E(): 4.8e-113, 63.08% id in 447 aa; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.926 |
| DIP1863 | sdaB | DIP1863 | DIP1359 | Putative hydrolase; Similar to Mycobacterium tuberculosis hypothetical protein Rv3042c TR:AAK47457 (EMBL:AL021287) (409 aa) fasta scores: E(): 3.1e-69, 54.54% id in 407 aa, and to Mycobacterium leprae putative phosphoserine phosphatase ML1727 TR:Q9CBQ6 (EMBL:AL583923) (411 aa) fasta scores: E(): 6.2e-66, 53.82% id in 405 aa. | L-serine dehydratase; Similar to Pseudomonas aeruginosa L-serine dehydratase SdaB or PA5379 SWALL:Q9HTI5 (EMBL:AE004950) (458 aa) fasta scores: E(): 3.5e-84, 53.99% id in 463 aa, and to Escherichia coli L-serine dehydratase 1 SdaA or B1814 SWALL:SDHL_ECOLI (SWALL:P16095) (454 aa) fasta scores: E(): 3e-70, 49.24% id in 461 aa; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.926 |
| DIP1863 | trpB1 | DIP1863 | DIP2351 | Putative hydrolase; Similar to Mycobacterium tuberculosis hypothetical protein Rv3042c TR:AAK47457 (EMBL:AL021287) (409 aa) fasta scores: E(): 3.1e-69, 54.54% id in 407 aa, and to Mycobacterium leprae putative phosphoserine phosphatase ML1727 TR:Q9CBQ6 (EMBL:AL583923) (411 aa) fasta scores: E(): 6.2e-66, 53.82% id in 405 aa. | Tryptophan synthase beta chain TrpB1; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.910 |
| glyA | DIP1863 | DIP0932 | DIP1863 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative hydrolase; Similar to Mycobacterium tuberculosis hypothetical protein Rv3042c TR:AAK47457 (EMBL:AL021287) (409 aa) fasta scores: E(): 3.1e-69, 54.54% id in 407 aa, and to Mycobacterium leprae putative phosphoserine phosphatase ML1727 TR:Q9CBQ6 (EMBL:AL583923) (411 aa) fasta scores: E(): 6.2e-66, 53.82% id in 405 aa. | 0.938 |
| glyA | ilvA | DIP0932 | DIP1579 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.959 |
| glyA | metX | DIP0932 | DIP0623 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.818 |
| glyA | sdaA | DIP0932 | DIP0490 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | L-serine dehydratase 1; Similar to Escherichia coli L-serine dehydratase 1 SdaA or B1814 SW:SDHL_ECOLI (P16095) (454 aa) fasta scores: E(): 4.8e-113, 63.08% id in 447 aa; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.959 |
| glyA | sdaB | DIP0932 | DIP1359 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | L-serine dehydratase; Similar to Pseudomonas aeruginosa L-serine dehydratase SdaB or PA5379 SWALL:Q9HTI5 (EMBL:AE004950) (458 aa) fasta scores: E(): 3.5e-84, 53.99% id in 463 aa, and to Escherichia coli L-serine dehydratase 1 SdaA or B1814 SWALL:SDHL_ECOLI (SWALL:P16095) (454 aa) fasta scores: E(): 3e-70, 49.24% id in 461 aa; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.956 |
| glyA | trpB1 | DIP0932 | DIP2351 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase beta chain TrpB1; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.907 |
| ilvA | DIP0630 | DIP1579 | DIP0630 | Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Putative methionine biosynthesis-related protein; Similar to Mycobacterium tuberculosis CDC1551 transulfuration enzyme family protein MT3443 TR:AAK47787 (EMBL:AE007151) (449 aa) fasta scores: E(): 4.8e-93, 56.94% id in 432 aa, and to Pseudomonas aeruginosa O-succinylhomoserine sulfhydrylase MetZ or PA3107 SW:METZ_PSEAE (P55218) (403 aa) fasta scores: E(): 2.7e-26, 39.31% id in 435 aa. | 0.807 |
| ilvA | DIP1863 | DIP1579 | DIP1863 | Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Putative hydrolase; Similar to Mycobacterium tuberculosis hypothetical protein Rv3042c TR:AAK47457 (EMBL:AL021287) (409 aa) fasta scores: E(): 3.1e-69, 54.54% id in 407 aa, and to Mycobacterium leprae putative phosphoserine phosphatase ML1727 TR:Q9CBQ6 (EMBL:AL583923) (411 aa) fasta scores: E(): 6.2e-66, 53.82% id in 405 aa. | 0.908 |
| ilvA | glyA | DIP1579 | DIP0932 | Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.959 |
| ilvA | metX | DIP1579 | DIP0623 | Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.821 |
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