STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hmuUIron-related transport system membrane protein; Almost identical to previously sequenced Corynebacterium diphtheriae HmuU TR:Q9XD88 (EMBL:AF109162) (350 aa) fasta scores: E(): 6.1e-120, 98% id in 350 aa, and highly similar to Corynebacterium ulcerans permease HmuU TR:Q9EZ56 (EMBL:AF304009) (350 aa) fasta scores: E(): 4.3e-100, 81.14% id in 350 aa; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (350 aa)    
Predicted Functional Partners:
hmuV
Iron-related transport system ATP-binding protein; Almost identical to the previously sequenced Corynebacterium diphtheriae HmuV TR:Q9XD87 (EMBL:AF109162) (277 aa) fasta scores: E(): 3.2e-88, 97.83% id in 277 aa, and to Escherichia coli iron (III) dicitrate transport ATP-binding protein FecE or B4287 SW:FECE_ECOLI (P15031) (255 aa) fasta scores: E(): 1.2e-23, 41.94% id in 236 aa.
 
 
 0.989
hmuT
Iron-related transport system receptor precursor protein; Identical to previously sequenced Corynebacterium diphtheriae HmuT precursor TR:Q9XD89 (EMBL:AF109162) (353 aa) fasta scores: E(): 3.9e-123, 98.86% id in 353 aa, and highly similar to Corynebacterium ulcerans hemin receptor precursor HmuT TR:Q9EZ57 (EMBL:AF304009) (351 aa) fasta scores: E(): 2.6e-99, 79.83% id in 352 aa.
 
 
 0.980
irp6C
ATP-binding protein Irp6C; Almost identical to previously sequenced Corynebacterium diphtheriae ATP-binding protein Irp6C SWALL:Q8VVA6 (EMBL:AY061890) (252 aa) fasta scores: E(): 1.4e-79, 99.6% id in 252 aa and similar to Escherichia coli iron FecE or B4287 SWALL:FECE_ECOLI (SWALL:P15031) (255 aa) fasta scores: E(): 5.7e-19, 37.64% id in 263 aa.
 
 
 0.875
DIP1085
Putative iron ABC transport system, ATP-binding protein; Similar to Bacillus subtilis ferrichrome transport ATP-binding protein FhuC SW:FHUC_BACSU (P49938) (269 aa) fasta scores: E(): 5.1e-24, 35.15% id in 256 aa, and to Escherichia coli iron(III)dicitrate transport ATP-binding protein FecE or B4287 SW:FECE_ECOLI (P15031) (255 aa) fasta scores: E(): 5.5e-24, 37.86% id in 243 aa.
 
 
 0.865
DIP1059
Similar to Streptomyces coelicolor putative iron-siderophore uptake system ATP-binding component SCI51.25C TR:Q9S215 (EMBL:AL109848) (301 aa) fasta scores: E(): 1.9e-42, 50.58% id in 255 aa, and to Escherichia coli ferric enterobactin transport ATP-binding protein fepC b0588 SW:FEPC_ECOLI (P23878) (271 aa) fasta scores: E(): 1.1e-41, 49.61% id in 262 aa.
 
 
 0.860
DIP0625
Putative membrane protein; Similar to the C-terminal region of Corynebacterium ulcerans HtaA TR:Q9EZ58 (EMBL:AF304009) (410 aa) fasta scores: E(): 4.9e-58, 54.14% id in 410 aa, and to Streptomyces coelicolor hypothetical 48.2 kDa protein SCC75A.17c TR:Q9RKQ7 (EMBL:AL133220) (477 aa) fasta scores: E(): 4.9e-06, 26.25% id in 579 aa.
 
    0.837
DIP0585
Similar to Bacillus subtilis ferrichrome transport ATP-binding protein FhuC SW:FHUC_BACSU (P49938) (269 aa) fasta scores: E(): 1.2e-37, 45.13% id in 257 aa, and to Escherichia coli iron FecE or B4287 SW:FECE_ECOLI (P15031) (255 aa) fasta scores: E(): 5e-32, 42.8% id in 250 aa.
 
 
 0.830
irp6A
Ferrisiderophore receptor Irp6A; Almost identical to previously sequenced Corynebacterium diphtheriae ferrisiderophore receptor Irp6A SWALL:Q8VVA8 (EMBL:AY061890) (395 aa) fasta scores: E(): 8.7e-146, 97.46% id in 395 aa.
 
 
 0.694
DIP0624
Putative membrane protein; No significant database matches.
  
  
 0.540
DIP0629
Membrane protein; Almost identical to previously sequenced Corynebacterium diphtheriae secreted protein precursor TR:Q9XD85 (EMBL:AF109162) (339 aa) fasta scores: E(): 2.9e-99, 89.21% id in 306 aa.
  
    0.496
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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