STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0640Conserved hypothetical protein; C-terminal region similar to C-terminal region of Mycobacterium leprae putative secreted protein ML0885 or MLCB268.32c TR:O69580 (EMBL:AL022602) (374 aa) fasta scores: E(): 4.6e-12, 37.57% id in 173 aa. (279 aa)    
Predicted Functional Partners:
DIP0639
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 45.7 kDa protein Rv3311 or MTV016.10 TR:O53362 (EMBL:AL021841) (420 aa) fasta scores: E(): 1.4e-25, 34.05% id in 417 aa.
       0.807
DIP0641
Hypothetical protein; No significant database matches.
       0.773
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
       0.705
DIP0643
Putative DNA-binding protein; No significant database matches.
       0.572
DIP0874
Putative secreted protein; Similar to Mycobacterium tuberculosis hypothetical 38.1 kDa protein Rv1009 or MTCI237.26 TR:O05594 (EMBL:Z94752) (362 aa) fasta scores: E(): 1.8e-39, 38.71% id in 372 aa.
   
  
 0.572
DIP0644
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 hydrolase, Ama/HipO/HyuC family MT3404 TR:AAK47747 (EMBL:AE007149) (389 aa) fasta scores: E(): 4.5e-74, 49.74% id in 388 aa.
       0.517
lpdA
Similar to Mycobacterium tuberculosis dihydrolipoamide dehydrogenase LpdA or Rv3303c or MTV016.02c TR:O53355 (EMBL:AL021841) (493 aa) fasta scores: E(): 5.8e-110, 64.04% id in 470 aa, and to Bacillus subtilis dihydrolipoamide dehydrogenase PdhD or AceD or CitL SW:DLD1_BACSU (P21880) (470 aa) fasta scores: E(): 1.2e-36, 31.47% id in 467 aa.
       0.497
DIP1135
Putative kinase; Similar to Mycobacterium tuberculosis hypothetical 46.7 kDa protein Rv2974c or MTCY349.13 TR:P95121 (EMBL:Z83018) (470 aa) fasta scores: E(): 4e-28, 33.402% id in 485 aa, and to Clostridium acetobutylicum predicted kinase related to hydroxyacetone kinase YloV ortholog CAC1735 TR:AAK79701 (EMBL:AE007682) (547 aa) fasta scores: E(): 3.8e-21, 25.690% id in 471 aa.
      
 0.474
ctaC
Putative cytochrome C oxidase precursor; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity).
      
 0.474
DIP1621
Similar to Mycobacterium leprae putative secreted protein ML0885 or MLCB268.32c TR:O69580 (EMBL:AL022602) (374 aa) fasta scores: E(): 1.7e-22, 36.2% id in 348 aa.
  
   
0.445
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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