STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypAPutative hydrogenase nickel incorporation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (121 aa)    
Predicted Functional Partners:
DIP0671
Similar to Rhodobacter capsulatus hydrogenase nickel incorporation protein HypB or HupM SW:HYPB_RHOCA (P26410) (335 aa) fasta scores: E(): 1.3e-34, 45.78% id in 249 aa, and to Escherichia coli hydrogenase isoenzymes nickel incorporation protein HypB or B2727 SW:HYPB_ECOLI (P24190) (290 aa) fasta scores: E(): 7.4e-34, 44.58% id in 231 aa.
 
 
 0.927
DIP0678
Putative hydrogenase operon protein; Similar to Azotobacter vinelandii probable hydrogenase expression/formation protein HypC or HupF SW:HYPC_AZOVI (P31881) (84 aa) fasta scores: E(): 8.5e-06, 36.25% id in 80 aa, and to Escherichia coli hydrogenase-2 operon protein HybG or B2990 or Z4344 or ECS3875 SW:HYBG_ECOLI (P37185) (82 aa) fasta scores: E(): 0.0017, 28.94% id in 76 aa.
 
  
 0.903
DIP0677
Similar to Methanococcus voltae methylviologen-reducing hydrogenase Vhu alpha subunit VhuA TR:Q00407 (EMBL:X61204) (420 aa) fasta scores: E(): 9e-06, 24.37% id in 398 aa.
 
  
 0.804
DIP0673
Similar to Bradyrhizobium japonicum uptake hydrogenase large subunit HupB or HupL SW:MBHL_BRAJA (P12636) (596 aa) fasta scores: E(): 2.8e-98, 45% id in 591 aa, and to Escherichia coli hydrogenase-1 large chain HyaB or B0973 SW:MBHL_ECOLI (P19927) (597 aa) fasta scores: E(): 2.5e-91, 41.25% id in 589 aa.
 
 
 0.775
hypC
Similar to Rhodobacter capsulatus hydrogenase expression/formation protein HypC SW:HYPC_RHOCA (P40428) (96 aa) fasta scores: E(): 4.7e-09, 50% id in 82 aa, and to Escherichia coli hydrogenase-2 operon protein HybG or B2990 or Z4344 or ECS3875 SW:HYBG_ECOLI (P37185) (82 aa) fasta scores: E(): 8e-08, 44% id in 75 aa.
 
  
 0.771
hypD
Similar to Escherichia coli hydrogenase isoenzymes formation protein HypD or B2729 SW:HYPD_ECOLI (P24192) (373 aa) fasta scores: E(): 4.1e-77, 51.73% id in 375 aa, and to Nostoc punctiforme HypD-like protein TR:Q9EYH5 (EMBL:AF325724) (392 aa) fasta scores: E(): 8.7e-94, 58.74% id in 366 aa.
 
  
 0.709
hypE
Similar to Rhodobacter capsulatus hydrogenase expression/formation protein HypE SW:HYPE_RHOCA (P26412) (340 aa) fasta scores: E(): 8e-46, 49.7% id in 336 aa, and to Escherichia coli hydrogenase isoenzymes formation protein HypE or B2730 SW:HYPE_ECOLI (P24193) (322 aa) fasta scores: E(): 5.7e-38, 43.03% id in 323 aa.
 
  
 0.702
DIP0669
Similar to Azotobacter chroococcum MCD 1 hydrogenase maturation protein HypF or HupY SW:HYPF_AZOCH (Q43950) (776 aa) fasta scores: E(): 2.5e-73, 37.62% id in 784 aa, and to Escherichia coli hydrogenase maturation protein HypF or HydA or B2712 SW:HYPF_ECOLI (P30131) (750 aa) fasta scores: E(): 1e-43, 38.82% id in 765 aa.
 
   
 0.692
DIP0997
Putative ATP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
   
   0.649
DIP0672
Similar to Azotobacter vinelandii uptake hydrogenase small subunit precursor HoxK SW:MBHS_AZOVI (P21950) (358 aa) fasta scores: E(): 4.6e-64, 45.75% id in 365 aa, and to Escherichia coli hydrogenase-1 small chain precursor HyaA or B0972 SW:MBHS_ECOLI (P19928) (372 aa) fasta scores: E(): 1.3e-58, 42.54% id in 369 aa.
 
  
 0.486
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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