STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0679Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 23.7 kDa protein Rv3268 or MTCY71.08 TR:P96873 (EMBL:Z92771) (229 aa) fasta scores: E(): 7.6e-11, 31.48% id in 235 aa. (220 aa)    
Predicted Functional Partners:
fas
Putative fatty acid synthase; Similar to the N-terminal region of Corynebacterium ammoniagenes fatty acid synthase Fas TR:Q04846 (EMBL:X64795) (3104 aa) fasta scores: E(): 0, 61.33% id in 3018 aa, and to the full length of Mycobacterium tuberculosis fatty acid synthase Rv2524c TR:AAK46907 (EMBL:Z83863) (3069 aa) fasta scores: E(): 1e-197, 51.37% id in 3083 aa, and of Corynebacterium glutamicum 3-oxoacyl-(acyl-carrier-protein) synthase CGL2495 SWALL:Q8NMS0 (EMBL:AP005281) (2993 aa) fasta scores: E(): 0, 67.35% id in 3008 aa.
  
 
 0.930
DIP0680
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3367 TR:AAK47708 (EMBL:AE007146) (497 aa) fasta scores: E(): 6e-73, 50.1% id in 469 aa.
     
 0.868
gltA
Citrate synthase; Similar to Corynebacterium glutamicum citrate synthase GltA SW:CISY_CORGL (P42457) (437 aa) fasta scores: E(): 2.5e-151, 87.52% id in 433 aa.
 
 
 0.823
DIP0791
Similar to Streptomyces coelicolor putative transmembrane transport protein SCI8.07c TR:Q9RJ46 (EMBL:AL132644) (544 aa) fasta scores: E(): 4.2e-82, 58.31% id in 547 aa; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
  
 0.752
DIP1075
Similar to Mycobacterium leprae hypothetical protein ML1706 TR:Q9CBR6 (EMBL:AL583923) (337 aa) fasta scores: E(): 4.5e-19, 32.26% id in 313 aa, and to Mycobacterium tuberculosis CDC1551 vitamin-b12 independent methionine synthase family protein MT3095 TR:AAK47424 (EMBL:AE007129) (337 aa) fasta scores: E(): 1.4e-18, 31.94% id in 313 aa, and to Mycobacterium tuberculosis hypothetical 34.2 kDa protein Rv3015c or MTV012.29C TR:O53262 (EMBL:AL021287) (337 aa) fasta scores: E(): 1.4e-18, 31.94% id in 313 aa.
  
    0.735
DIP2160
Modular polyketide synthase; Similar to Streptomyces verticillus polyketide synthase BlmVIII (bleomycin biosynthesis) TR:Q9FB25 (EMBL:AF210249) (1841 aa) fasta scores: E(): 1.3e-72, 27.240% id in 1931 aa, and to Streptomyces noursei nystatin biosynthesis polyketide synthase Nys TR:Q9L4W3 (EMBL:AF263912) (11096 aa) fasta scores: E(): 4e-71, 33.107% id in 882 aa, and to Amycolatopsis mediterranei rifamycin polyketide synthase TR:Q9F847 (EMBL:AF262754) (1265 aa) fasta scores: E(): 7.7e-61, 31.042% id in 902 aa.
  
 
 0.700
cstA1
Similar to Escherichia coli carbon starvation protein A CstA SW:CSTA_ECOLI (P15078) (701 aa) fasta scores: E(): 2.3e-129, 53.01% id in 696 aa, and to Mycobacterium tuberculosis carbon starvation protein A homologue Rv3063 SW:CSTA_MYCTU (P95095) (758 aa) fasta scores: E(): 5.9e-175, 61.47% id in 719 aa. CDS contains an extended N-terminus in comparison to the E. coli orthologue.
   
    0.651
DIP0790
Putative membrane protein; Similar to Streptomyces coelicolor putative integral membrane protein SCI8.08c TR:Q9RJ45 (EMBL:AL132644) (124 aa) fasta scores: E(): 2.6e-18, 43.63% id in 110 aa.
 
  
 0.632
DIP0681
Putative glycosyl transferase; Similar to Mycobacterium tuberculosis CDC1551 glycosyl transferase MT3365 TR:AAK47706 (EMBL:AE007146) (301 aa) fasta scores: E(): 5.1e-56, 52.12% id in 282 aa.
       0.630
DIP1157
Conserved hypothetical protein; N-terminal region similar to Streptomyces coelicolor hypothetical 18.8 kDa protein SC9H11.26c SWALL:Q9KYL5 (EMBL:AL356592) (177 aa) fasta scores: E(): 9.8e-11, 35.13% id in 148 aa. Note: Possible colied-coil region at C-terminal domain from residue 242 till the end.
  
    0.615
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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