Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DIP0688Conserved hypothetical protein; Similar in its N-terminal region to Mycobacterium tuberculosis hypothetical 35.3 kDa protein Rv3256c or MTV015.01c or MTCY20b11.31c TR:O05899 (EMBL:Z95121) (346 aa) fasta scores: E(): 5.1e-06, 27.69% id in 260 aa. (335 aa)    
Predicted Functional Partners:
ptsG
Similar to Corynebacterium glutamicum PTS system, glucose-specific IIABC component PtsG SWALL:PTGA_CORGL (SWALL:Q45298) (674 aa) fasta scores: E(): 2.8e-59, 44.91% id in 688 aa, and to Staphylococcus xylosus PTS system, sucrose-specific IIBC component ScrA SWALL:PTSB_STAXY (SWALL:P51184) (480 aa) fasta scores: E(): 8e-26, 27.73% id in 494 aa.
  
  
 0.849
DIP0687
Putative phosphomannomutase; Similar to Mycobacterium tuberculosis CDC1551 phosphomannomutase MT3355 TR:AAK47697 (EMBL:AE007145) (465 aa) fasta scores: E(): 3.1e-106, 63.27% id in 452 aa, and to Salmonella montevideo phosphomannomutase ManB or CpsG or RfbL SW:MANB_SALMO (Q01411) (456 aa) fasta scores: E(): 1.3e-53, 38.22% id in 463 aa.
  
  
 0.813
DIP0689
Putative mannose-phosphate isomerase; Similar to Mycobacterium tuberculosis CDC1551 mannose-6-phosphate isomerase MT3353 TR:AAK47695 (EMBL:AE007145) (408 aa) fasta scores: E(): 1.6e-57, 47.43% id in 409 aa, and to Escherichia coli mannose-6-phosphate isomerase ManA or Pmi or B1613 SW:MANA_ECOLI (P00946) (391 aa) fasta scores: E(): 1.7e-24, 38.34% id in 399 aa.
  
    0.806
DIP2264
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 123.1 kDa protein Rv1251c or MT1290 or MTV006.23c SWALL:O50466 (EMBL:AL021006) (1139 aa) fasta scores: E(): 1.6, 26.47% id in 544 aa.
  
     0.753
DIP1795
Putative exported protein; Poor database matches. Similar to the C-terminal region of Streptomyces coelicolor putative secreted protein SC1C2.11 TR:O86512 (EMBL:AL031124) (450 aa) fasta scores: E(): 0.47, 27.13% id in 269 aa.
  
     0.739
DIP0274
Putative mutase; Similar to Streptomyces coelicolor putative phosphomannomutase SCK13.08c TR:Q9AD82 (EMBL:AL512667) (549 aa) fasta scores: E(): 7.9e-86, 46.75% id in 554 aa.
  
  
 0.710
DIP0598
Putative membrane protein; No significant database matches.
  
     0.708
DIP2134
Conserved hypothetical protein; N-terminus similar to those from other actinomycetes eg. Saccharopolyspora erythraea Orf122 protein TR:Q54106 (EMBL:X92556) (121 aa) fasta scores: E(): 0.0076, 31.15% id in 138 aa, and to Streptomyces coelicolor hypothetical 30.8 kDa protein SCE6.30c TR:Q9KZR0 (EMBL:AL353832) (277 aa) fasta scores: E(): 0.02, 36.76% id in 68 aa.
  
     0.708
DIP1401
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 17.6 kDa protein Rv2698 or MTCY05A6.19 TR:O07200 (EMBL:Z96072) (161 aa) fasta scores: E(): 1.9e-21, 45.28% id in 159 aa, and to Mycobacterium leprae U1764I ML12027 TR:Q49991 (EMBL:U15181) (157 aa) fasta scores: E(): 3e-19, 41.77% id in 158 aa.
  
     0.703
DIP1995
Putative membrane protein; Weakly similar to the N-terminal regions of Mycobacterium leprae putative membrane protein ML0228 TR:O69526 (EMBL:AL023093) (432 aa) fasta scores: E(): 0.025, 25.15% id in 318 aa, and to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3709 TR:AAK48067 (EMBL:AE007170) (397 aa) fasta scores: E(): 0.071, 23.51% id in 336 aa.
  
     0.691
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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