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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtrA2Putative two component system response regulator; Similar to Mycobacterium tuberculosis MtrA protein or Rv3246c or MTCY20B11.21c TR:Q50447 (EMBL:Z95121) (228 aa) fasta scores: E(): 7.6e-61, 70.66% id in 225 aa, and to Streptomyces coelicolor transcriptional regulatory protein AfsQ1 or 2SCK8.33c SW:AFQ1_STRCO (Q04942) (225 aa) fasta scores: E(): 2.4e-36, 45.2% id in 219 aa. (232 aa)    
Predicted Functional Partners:
mtrB
Putative two component system sensor kinase; Similar to Mycobacterium tuberculosis MtrB or Rv3245c or MTCY20B11.20c TR:O05890 (EMBL:Z95121) (567 aa) fasta scores: E(): 4.6e-89, 53.73% id in 482 aa, and to Streptomyces coelicolor sensor protein AfsQ2 or 2SCK8.32c SW:AFQ2_STRCO (Q04943) (535 aa) fasta scores: E(): 1.4e-23, 30.64% id in 447 aa.
 0.999
DIP0390
Putative two component system sensor kinase; Similar to Mycobacterium tuberculosis sensor-like histidine kinase SenX3 or Rv0490 or MT0509 or MTCY20G9.16 SW:SEX3_MYCTU (Q11155) (410 aa) fasta scores: E(): 3.6e-60, 48.84% id in 389 aa.
 
 0.901
DIP1935
Putative two somponent system sensor kinase protein; C-terminal region is similar to Mycobacterium tuberculosis hypothetical protein Rv0758 TR:P71815 (EMBL:Z80226) (485 aa) fasta scores: E(): 7.7e-38, 42.88% id in 471 aa, and to Bacillus halodurans two-component sensor histidine kinase BH0373 TR:Q9KFU8 (EMBL:AP001508) (459 aa) fasta scores: E(): 3.7e-29, 30.81% id in 464 aa.
 
 0.900
DIP0287
Similar to Escherichia coli sensor protein RcsC or B2218 SW:RCSC_ECOLI (P14376) (933 aa) fasta scores: E(): 5.5e-10, 26.339% id in 224 aa, and to Pseudomonas syringae sensor protein GacS or LemA SW:GACS_PSESY (P48027) (907 aa) fasta scores: E(): 2e-09, 27.530% id in 247 aa.
 
 
 0.875
DIP0855
Putative two component system sensor kinase; Similar to Corynebacterium glutamicum sensor kinase TR:Q9F160 (EMBL:AF119221) (455 aa) fasta scores: E(): 6.5e-71, 46.98% id in 447 aa, and to Burkholderia pseudomallei sensor protein IrlS SW:IRLS_BURPS (O31396) (464 aa) fasta scores: E(): 4.6e-18, 26% id in 446 aa.
 
 0.836
DIP0063
Putative two-component system sensor protein; Similar to Escherichia coli sensor protein BaeS or B2078 SW:BAES_ECOLI (P30847) (467 aa) fasta scores: E(): 1.8e-28, 33.333% id in 372 aa.
   0.795
lpqB
Putative secreted protein; Similar to Mycobacterium tuberculosis hypothetical 61.2 kDa protein LpqB or Rv3244c or MTCY20B11.19c TR:O05889 (EMBL:Z95121) (583 aa) fasta scores: E(): 1.6e-14, 28.76% id in 591 aa.
     
 0.764
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
       0.731
tmk
Putative thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
       0.731
DIP0697
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 22.5 kDa protein Rv3242c or MTCY20B11.17c TR:O05887 (EMBL:Z95121) (213 aa) fasta scores: E(): 8.3e-21, 41.5% id in 212 aa.
  
    0.644
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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