STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtrBPutative two component system sensor kinase; Similar to Mycobacterium tuberculosis MtrB or Rv3245c or MTCY20B11.20c TR:O05890 (EMBL:Z95121) (567 aa) fasta scores: E(): 4.6e-89, 53.73% id in 482 aa, and to Streptomyces coelicolor sensor protein AfsQ2 or 2SCK8.32c SW:AFQ2_STRCO (Q04943) (535 aa) fasta scores: E(): 1.4e-23, 30.64% id in 447 aa. (480 aa)    
Predicted Functional Partners:
mtrA2
Putative two component system response regulator; Similar to Mycobacterium tuberculosis MtrA protein or Rv3246c or MTCY20B11.21c TR:Q50447 (EMBL:Z95121) (228 aa) fasta scores: E(): 7.6e-61, 70.66% id in 225 aa, and to Streptomyces coelicolor transcriptional regulatory protein AfsQ1 or 2SCK8.33c SW:AFQ1_STRCO (Q04942) (225 aa) fasta scores: E(): 2.4e-36, 45.2% id in 219 aa.
 0.999
DIP0286
Two-component regulatory protein; Similar to Klebsiella pneumoniae phosphate regulon transcriptional regulatory protein PhoB SW:PHOB_KLEPN (P45605) (229 aa) fasta scores: E(): 1.7e-25, 40.708% id in 226 aa, to Shigella dysenteriae phosphate regulon transcriptional regulatory protein PhoB SW:PHOB_SHIDY (P45606) (229 aa) fasta scores: E(): 6.5e-25, 40.265% id in 226 aa, and to Escherichia coli phosphate regulon transcriptional regulatory protein PhoB or B0399 or Z0497 or ECS0449 SW:PHOB_ECOLI (P08402) (229 aa) fasta scores: E(): 6.5e-25, 40.265% id in 226 aa.
 
 0.922
lpqB
Putative secreted protein; Similar to Mycobacterium tuberculosis hypothetical 61.2 kDa protein LpqB or Rv3244c or MTCY20B11.19c TR:O05889 (EMBL:Z95121) (583 aa) fasta scores: E(): 1.6e-14, 28.76% id in 591 aa.
 
    0.886
regX3
Putative two component system response regulator; Similar to Mycobacterium tuberculosis sensory transduction protein RegX3 or Rv0491 or MT0510 or MTCY20G9.17 SW:RGX3_MYCTU (Q11156) (227 aa) fasta scores: E(): 4e-68, 80.97% id in 226 aa.
 
 0.871
DIP0854
Putative two component system response regulator; Similar to Corynebacterium glutamicum response regulator TR:Q9F161 (EMBL:AF119221) (232 aa) fasta scores: E(): 2.4e-67, 79.31% id in 232 aa, and to Pseudomonas syringae transcriptional activator protein CopR SW:COPR_PSESM (Q02540) (227 aa) fasta scores: E(): 1.9e-32, 48% id in 225 aa.
 
 0.871
DIP0064
Putative two-component system response regulator; Similar to Enterococcus faecalis VicR protein TR:Q9REA7 (EMBL:AJ012050) (283 aa) fasta scores: E(): 5.5e-35, 44.978% id in 229 aa, to Bacillus subtilis alkaline phosphatase synthesis transcriptional regulatory protein PhoP SW:PHOP_BACSU (P13792) (240 aa) fasta scores: E(): 3e-34, 42.918% id in 233 aa, and to Bacillus subtilis hypothetical sensory transduction protein YycF SW:YYCF_BACSU (P37478) (235 aa) fasta scores: E(): 1.8e-33, 43.478% id in 230 aa.
 
 
 0.859
DIP0697
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 22.5 kDa protein Rv3242c or MTCY20B11.17c TR:O05887 (EMBL:Z95121) (213 aa) fasta scores: E(): 8.3e-21, 41.5% id in 212 aa.
 
    0.856
DIP1936
Putative two component system response regulator protein; Similar to Bacillus subtilis alkaline phosphatase synthesis transcriptional regulatory protein PhoP SW:PHOP_BACSU (P13792) (240 aa) fasta scores: E(): 1.3e-32, 42.37% id in 236 aa, and to Mycobacterium tuberculosis hypothetical PhoP-like protein Rv0757 TR:AAK45023 (EMBL:Z80226) (240 aa) fasta scores: E(): 3.2e-57, 66.37% id in 226 aa.
 
 0.842
odhA
2-oxoglutarate dehydrogenase, E1 and E2 components; Similar to Corynebacterium glutamicum 2-oxoglutarate dehydrogenase OdhA TR:P96746 (EMBL:D84102) (1257 aa) fasta scores: E(): 0, 77.37% id in 1242 aa, and to Mycobacterium leprae 2-oxoglutarate dehydrogenase, E1 and E2 components OdhA or ML1095 TR:Q9CC97 (EMBL:AL583920) (1260 aa) fasta scores: E(): 0, 59.37% id in 1253 aa. Similar in the N-terminus to Escherichia coli dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex (E2) SucB or B0727 or Z0881 or ECS0752 SW:ODO2_ECOLI (P07016) blastp scores: E(): 4 [...]
   
 0.764
DIP0021
Similar to Streptomyces coelicolor probable solute-binding lipoprotein SC8F11.05 TR:Q9KZH3 (EMBL:AL353864) (340 aa) fasta scores: E(): 2.8e-63, 54.98% id in 331 aa.
    
 
 0.684
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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