STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0704Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 48.4 kDa protein DesA3 or Rv3229c or MTCY20B11.04c TR:O05874 (EMBL:Z95121) (427 aa) fasta scores: E(): 1.5e-86, 52.59% id in 405 aa. (426 aa)    
Predicted Functional Partners:
DIP0703
Putative oxidoreductase; Similar to Mycobacterium tuberculosis hypothetical 40.8 kDa protein Rv3230c or MTCY20B11.05c TR:O05875 (EMBL:Z95121) (380 aa) fasta scores: E(): 4.8e-60, 49.14% id in 350 aa, and to Escherichia coli NADH oxidoreductase Hcr or B0872 SW:HCR_ECOLI (P75824) (322 aa) fasta scores: E(): 1.9e-13, 28.71% id in 296 aa.
 
 0.999
fas
Putative fatty acid synthase; Similar to the N-terminal region of Corynebacterium ammoniagenes fatty acid synthase Fas TR:Q04846 (EMBL:X64795) (3104 aa) fasta scores: E(): 0, 61.33% id in 3018 aa, and to the full length of Mycobacterium tuberculosis fatty acid synthase Rv2524c TR:AAK46907 (EMBL:Z83863) (3069 aa) fasta scores: E(): 1e-197, 51.37% id in 3083 aa, and of Corynebacterium glutamicum 3-oxoacyl-(acyl-carrier-protein) synthase CGL2495 SWALL:Q8NMS0 (EMBL:AP005281) (2993 aa) fasta scores: E(): 0, 67.35% id in 3008 aa.
  
  
 0.862
menD
Putative menaquinone biosynthesis protein; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
      
 0.831
menH
Putative ubiquinone/menaquinone biosynthesis methlytransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
      
 0.831
DIP0702
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 17.8 kDa protein Rv3231c or MTCY20B11.06c TR:O05876 (EMBL:Z95121) (169 aa) fasta scores: E(): 2.4e-25, 53.52% id in 170 aa.
       0.614
DIP0701
Conserved hypothetical protein; Similar to C-terminal region of Mycobacterium tuberculosis CDC1551 hydrolase, haloacid dehalogenase-like family MT3486 TR:AAK47822 (EMBL:AE007155) (217 aa) fasta scores: E(): 0.0053, 32.35% id in 136 aa.
       0.607
DIP2179
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 27.5 kDa protein Rv0224c or MTCY08D5.19c TR:P96406 (EMBL:Z92669) (254 aa) fasta scores: E(): 2.9e-56, 63.41% id in 246 aa, and to Streptomyces coelicolor putative methyltransferase SCC53.08c TR:Q9KXK3 (EMBL:AL357591) (244 aa) fasta scores: E(): 7.1e-06, 32.94% id in 173 aa.
  
   
 0.545
DIP2160
Modular polyketide synthase; Similar to Streptomyces verticillus polyketide synthase BlmVIII (bleomycin biosynthesis) TR:Q9FB25 (EMBL:AF210249) (1841 aa) fasta scores: E(): 1.3e-72, 27.240% id in 1931 aa, and to Streptomyces noursei nystatin biosynthesis polyketide synthase Nys TR:Q9L4W3 (EMBL:AF263912) (11096 aa) fasta scores: E(): 4e-71, 33.107% id in 882 aa, and to Amycolatopsis mediterranei rifamycin polyketide synthase TR:Q9F847 (EMBL:AF262754) (1265 aa) fasta scores: E(): 7.7e-61, 31.042% id in 902 aa.
  
 
 0.513
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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