Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DIP0708Putative secreted protein; Similar to Escherichia coli protein YbaK or B0481 SW:YBAK_ECOLI (P37175) (159 aa) fasta scores: E(): 1.2e-21, 46.49% id in 157 aa; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (167 aa)    
Predicted Functional Partners:
rpoE
Similar to Mycobacterium tuberculosis RNA polymerase sigma-E factor RpoE or SigH or Rv3223c or MT3320 or MTCY07D11.03 SW:RPOE_MYCTU (O05843) (216 aa) fasta scores: E(): 1e-44, 70.33% id in 182 aa; Belongs to the sigma-70 factor family. ECF subfamily.
       0.693
DIP0710
Similar to Streptomyces coelicolor anti-sigma factor RsrA TR:Q9RL96 (EMBL:AJ010320) (105 aa) fasta scores: E(): 5.5e-06, 35.71% id in 70 aa.
       0.586
tilS
Conserved hypothetical protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
      
 0.493
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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