STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0729Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 49.4 kDa protein Rv3195 or MTV014.39 TR:O53341 (EMBL:AL021646) (472 aa) fasta scores: E(): 5.1e-65, 45.37% id in 432 aa. (463 aa)    
Predicted Functional Partners:
DIP0260
Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
   
  
 0.887
DIP1926
Putative prolyl oligopeptidase; Similar to Mycobacterium tuberculosis CDC1551 protease II MT0805 TR:AAK45047 (EMBL:AE006971) (718 aa) fasta scores: E(): 1.1e-159, 55.68% id in 695 aa, and to Mycobacterium leprae ML2226 TR:O05748 (EMBL:Z95151) (724 aa) fasta scores: E(): 8.2e-148, 52.36% id in 699 aa.
   
  
 0.846
clpP2
ATP-dependent Clp protease proteolytic subunit 2; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
  
 0.790
DIP0730
Similar to Mycobacterium leprae putative secreted protein ML0643 TR:Q9CCM7 (EMBL:AL583919) (340 aa) fasta scores: E(): 5.2e-46, 43.42% id in 350 aa.
 
     0.780
DIP1642
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 26.9 kDa protein Rvv2219 precursor or MT2276 or MTCY190.30 SW:YM19_MYCTU (Q10405) (250 aa) fasta scores: E(): 2.4e-36, 42.8% id in 250 aa.
  
     0.759
DIP1402
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2773 TR:AAK47088 (EMBL:AE007106) (100 aa) fasta scores: E(): 1.6e-17, 57% id in 100 aa, and to Streptomyces coelicolor hypothetical 11.0 kDa protein SC2E9.05 TR:O54130 (EMBL:AL021530) (98 aa) fasta scores: E(): 4.9e-14, 49.49% id in 99 aa.
  
     0.745
rbpA
Conserved hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family.
  
     0.738
DIP1207
Putative transcriptional regulator; Similar to Mycobacterium tuberculosis hypothetical 24.0 kDa protein Rv1830 or MT1879 or MTCY1A11.13c SWALL:YI30_MYCTU (SWALL:Q50603) (225 aa) fasta scores: E(): 1.5e-41, 72.98% id in 174 aa, and to Bacillus subtilis regulatory protein GlnR SWALL:GLNR_BACSU (SWALL:P37582) (135 aa) fasta scores: E(): 0.22, 29.16% id in 72 aa.
  
     0.697
DIP1921
Similar to Corynebacterium ammoniagenes hypothetical protein Orf3 TR:Q9RHY2 (EMBL:AB003158) (132 aa) fasta scores: E(): 4.5e-26, 61.15% id in 121 aa, and to Mycobacterium tuberculosis hypothetical protein Rv0807 TR:O06627 (EMBL:Z95618) (129 aa) fasta scores: E(): 2.3e-24, 57.48% id in 127 aa.
  
     0.694
DIP1632
Putative membrane protein; Similar to Streptomyces coelicolor putative integral membrane protein SC5F7.32 TR:Q9S2R7 (EMBL:AL096872) (251 aa) fasta scores: E(): 4.8e-10, 30.45% id in 220 aa.
  
     0.687
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: medium (64%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.