STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pycBSimilar to Methanococcus jannaschii pyruvate carboxylase subunit B PycB or MJ1231 SW:PYCB_METJA (Q58628) (567 aa) fasta scores: E(): 1.8e-88, 50.81% id in 490 aa, and to Propionibacterium freudenreichii shermanii biotin carboxyl carrier protein of methylmalonyl-CoA carboxyl-transferase TR:Q05618 (EMBL:L06488) (519 aa) fasta scores: E(): 1.2e-108, 66.15% id in 520 aa. (493 aa)    
Predicted Functional Partners:
accBC
Similar to Corynebacterium glutamicum acyl coenzyme A carboxylase AccBC TR:P71122 (EMBL:U35023) (591 aa) fasta scores: E(): 1.5e-188, 85.47% id in 592 aa, and to Mycobacterium leprae acetyl-/propionyl-coenzyme A carboxylase alpha chain [includes: biotin carboxylase (EC 6.3.4.14); biotin carboxyl carrier protein(BCCP)] BccA or ML0726 or B1308_C1_129 SW:BCCA_MYCLE (P46392) (598 aa) fasta scores: E(): 1.1e-159, 72.46% id in 592 aa.
   
 0.992
DIP0742
Putative decarboxylase; Similar to Propionibacterium freudenreichii shermanii biotin carboxyl carrier protein of methylmalonyl-CoA carboxyl- transferase SW:BCCP_PROFR (P02904) (123 aa) fasta scores: E(): 2.6e-15, 49.18% id in 122 aa.
 
 
  0.991
mmdA
Similar to Propionigenium modestum methylmalonyl-CoA decarboxylase, alpha-subunit MmdA TR:O54028 (EMBL:AJ002015) (512 aa) fasta scores: E(): 2.2e-105, 54.1% id in 512 aa, and to Bacillus subtilis putative propionyl-CoA carboxylase beta chain YqjD SW:PCCB_BACSU (P54541) (506 aa) fasta scores: E(): 9.2e-91, 50.1% id in 497 aa.
    
 0.981
DIP0741
Hypothetical protein; No significant database matches.
    
  0.978
pccB1
Propionyl CoA carboxylase beta chain 1; Similar to Corynebacterium glutamicum DtsR2 protein TR:O87201 (EMBL:AB018531) (537 aa) fasta scores: E(): 2e-182, 87.87% id in 536 aa, and to Saccharopolyspora erythraea propionyl-CoA carboxylase beta chain PccB SW:PCCB_SACER (P53003) (546 aa) fasta scores: E(): 5.2e-137, 64.83% id in 546 aa. Possible duplication of DIP0660 (69.309% identity in 492 aa overlap).
    
 0.907
pccB2
propionyl-CoA carboxylase beta chain 2; Similar to Corynebacterium glutamicum DtsR1 protein TR:O88155 (EMBL:AB018531) (543 aa) fasta scores: E(): 1.5e-173, 81.76% id in 543 aa, and to Saccharopolyspora erythraea propionyl-CoA carboxylase beta chain PccB SW:PCCB_SACER (P53003) (546 aa) fasta scores: E(): 2.7e-127, 59.89% id in 546 aa. Possible duplication of DIP0658 (69.309% identity in 492 aa overlap).
    
 0.907
pta
Phosphate acetyltransferase; Highly similar in its C-terminal region to Corynebacterium glutamicum phosphate acetyltransferase Pta SWALL:PTA_CORGL (SWALL:P77844) (329 aa) fasta scores: E(): 6.9e-94, 78.22% id in 326 aa, similar to the C-terminal region of Mycobacterium tuberculosis phosphate acetyltransferase Pta or Rv0408 or MT0421 or MTCY22G10.04 SWALL:PTA_MYCTU (SWALL:P96254) (690 aa) fasta scores: E(): 4.8e-68, 48.67% id in 452 aa, and similar to the C-terminal region of Escherichia coli phosphate acetyltransferase Pta or B2297 SWALL:PTA_ECOLI (SWALL:P39184) (713 aa) fasta scores: [...]
     
 0.907
DIP1057
Putative methylmalonyl-CoA epimerase; Similar to Mycobacterium leprae B1549_F2_87 ML1157 TR:Q49717 (EMBL:U00014) (155 aa) fasta scores: E(): 1.2e-28, 55.47% id in 137 aa, and to Mycobacterium tuberculosis CDC1551 4-hydroxyphenylpyruvate dioxygenase C terminal domain containing protein MT1364 TR:AAK45627 (EMBL:AE007009) (152 aa) fasta scores: E(): 3e-27, 53.28% id in 137 aa, and to Pyrococcus horikoshii methylmalonyl-CoA epimerase PHO272 TR:AAK52053 (EMBL:AF364548) (136 aa) fasta scores: E(): 9.8e-13, 38.63% id in 132 aa, and to Homo sapiens methylmalonyl-CoA epimerase TR:AAK52052 (EMBL [...]
    
  0.903
DIP1811
Similar to Rhizobium loti dehydrogenase; zinc-binding alcohol dehydrogenase; NADPH quinone oxidoreductase; oxidoreductase MLR3212 TR:Q98GR0 (EMBL:AP003001) (329 aa) fasta scores: E(): 4.7e-52, 47.67% id in 323 aa, and to Pseudomonas aeruginosa probable oxidoreductase PA1833 TR:Q9I2R2 (EMBL:AE004609) (330 aa) fasta scores: E(): 5.9e-45, 43.82% id in 324 aa.
    
  0.903
DIP0657
Hypothetical protein; No significant database matches.
     
  0.900
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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