STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
DIP0749Putative cell division protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (300 aa)    
Predicted Functional Partners:
ftsE
Cell division ATP-binding protein; Part of the ABC transporter FtsEX involved in cellular division.
 
 
 0.998
DIP1281
Putative invasion protein; Similar to Mycobacterium tuberculosis hypothetical 49.8 kDa protein Rv1477 or MT1524 or MTV007.24 SWALL:O53168 (EMBL:AL021184) (472 aa) fasta scores: E(): 3.5e-21, 31.88% id in 577 aa, and C-terminal half similar to the whole length of Mycobacterium tuberculosis hypothetical invasion protein Inv1 SWALL:O33171 (EMBL:AF006054) (277 aa) fasta scores: E(): 1e-17, 39.5% id in 281 aa. Note: Contains two possible colied-coil region at residues 102..130 and 182..360.
 
 
 
 0.832
ftsZ
Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
  
 0.791
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
  
  
 0.724
DIP0747
Putative membrane protein; Similar to Neisseria gonorrhoeae putative efflux pump component MtrF TR:Q9RNX1 (EMBL:AF176821) (522 aa) fasta scores: E(): 2.4e-35, 40.03% id in 527 aa, and to Escherichia coli aminobenzoyl-glutamate transport protein AbgT or B1336 SW:ABGT_ECOLI (P46133) (510 aa) fasta scores: E(): 1.7e-28, 34.72% id in 527 aa.
       0.657
DIP2375
Putative hydrolase; Similar to Mycobacterium tuberculosis putative hydrolase CwlM or Rv3915 or MTV028.06 TR:O53593 (EMBL:AL021426) (406 aa) fasta scores: E(): 5.4e-78, 52.38% id in 399 aa, and to Bacillus subtilis N-acetylmuramoyl-L-alanine amidase CwlB precursor or LytC SW:CWLB_BACSU (Q02114) (496 aa) fasta scores: E(): 2.8e-07, 25.62% id in 199 aa.
 
   
 0.652
DIP1596
Putative cell division protein precursor; Essential cell division protein.
    
 
 0.627
DIP1599
Putative cell division protein; Similar to Corynebacterium glutamicum FtsW protein TR:Q9L4H4 (EMBL:AJ242646) (490 aa) fasta scores: E(): 9.6e-78, 48.85% id in 481 aa, and to Escherichia coli cell division protein FtsW or B0089 or Z0099 or ECS0093 SW:FTSW_ECOLI (P16457) (414 aa) fasta scores: E(): 1e-21, 32.53% id in 375 aa; Belongs to the SEDS family.
  
  
 0.519
mltG
Putative secreted protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
  
    0.512
ftsY
Putative low affinity ammonium uptake protein (pseudogene); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
     
 0.511
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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