STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0772Similar to Mycobacterium tuberculosis CDC1551 ATP-dependent DNA helicase, putative MT0884 TR:AAK45125 (EMBL:AE006976) (542 aa) fasta scores: E(): 1.5e-161, 74.63% id in 544 aa. (554 aa)    
Predicted Functional Partners:
DIP0773
Putative DNA-binding protein; Similar to Mycobacterium leprae possible DNA-binding protein ML2156 TR:Q9CBE1 (EMBL:AL583924) (753 aa) fasta scores: E(): 1.2e-60, 33.5% id in 758 aa.
 
     0.938
DIP0771
Putative aminotransferase (pseudogene); FPrintScan hit to PR00753, 1-aminocyclopropane-1-carboxylate synthase signature.
  
    0.845
DIP1859
DeaD/DeaH family helicase; Similar to Escherichia coli probable ATP-dependent helicase DinG SW:DING_ECOLI (P27296) (716 aa) fasta scores: E(): 5.6e-15, 27.57% id in 689 aa, and to Mycobacterium tuberculosis probable ATP-dependent helicase DinG homologue Rv1329c SW:DING_MYCTU (Q10640) (664 aa) fasta scores: E(): 2.2e-131, 55.84% id in 659 aa.
   
 0.770
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  0.756
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.745
rpoZ
Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
  0.744
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.657
DIP0774
Similar to Mycobacterium leprae hypothetical protein ML2155 TR:Q9CBE2 (EMBL:AL583924) (74 aa) fasta scores: E(): 7.5e-08, 54.09% id in 61 aa.
       0.650
rpoC
DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  0.447
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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