Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DIP0773Putative DNA-binding protein; Similar to Mycobacterium leprae possible DNA-binding protein ML2156 TR:Q9CBE1 (EMBL:AL583924) (753 aa) fasta scores: E(): 1.2e-60, 33.5% id in 758 aa. (772 aa)    
Predicted Functional Partners:
DIP0772
Similar to Mycobacterium tuberculosis CDC1551 ATP-dependent DNA helicase, putative MT0884 TR:AAK45125 (EMBL:AE006976) (542 aa) fasta scores: E(): 1.5e-161, 74.63% id in 544 aa.
 
     0.935
DIP0771
Putative aminotransferase (pseudogene); FPrintScan hit to PR00753, 1-aminocyclopropane-1-carboxylate synthase signature.
       0.741
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.711
rpoC
DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.711
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.711
rpoZ
Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
   0.701
DIP0774
Similar to Mycobacterium leprae hypothetical protein ML2155 TR:Q9CBE2 (EMBL:AL583924) (74 aa) fasta scores: E(): 7.5e-08, 54.09% id in 61 aa.
       0.698
DIP0702
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 17.8 kDa protein Rv3231c or MTCY20B11.06c TR:O05876 (EMBL:Z95121) (169 aa) fasta scores: E(): 2.4e-25, 53.52% id in 170 aa.
  
     0.664
sigA
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
   0.575
sigB
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
    
   0.575
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.