STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0779Conserved hypothetical protein; Similar to Mycobacterium leprae hypothetical 28.2 kDa protein ML2142 or MLCB57.29 TR:O33058 (EMBL:Z99494) (269 aa) fasta scores: E(): 5.4e-18, 43.55% id in 225 aa. (254 aa)    
Predicted Functional Partners:
DIP1686
Conserved hypothetical protein; Similar to Mycobacterium leprae hypothetical 15.2 kDa protein ML1649 or MLCB1243.26 TR:O69479 (EMBL:AL023635) (140 aa) fasta scores: E(): 4.1e-24, 56.55% id in 122 aa.
  
     0.745
DIP0777
Putative secreted protein; Similar to Mycobacterium tuberculosis hypothetical 17.8 kDa protein Rv0875c precursor or MT0898 or MTCY31.03c SW:Y875_MYCTU (Q10537) (162 aa) fasta scores: E(): 6e-05, 25.92% id in 162 aa.
       0.709
DIP0778
Putative secreted protein; Similar to Deinococcus radiodurans glutamine cyclotransferase DR0112 TR:Q9RY39 (EMBL:AE001874) (294 aa) fasta scores: E(): 1e-28, 40.84% id in 284 aa.
       0.709
DIP0780
Putative membrane protein; Similar to Streptomyces coelicolor putative integral membrane protein SCD12A.17 TR:Q9KXM3 (EMBL:AL357524) (485 aa) fasta scores: E(): 4.6e-64, 46.04% id in 493 aa.
       0.642
DIP1402
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2773 TR:AAK47088 (EMBL:AE007106) (100 aa) fasta scores: E(): 1.6e-17, 57% id in 100 aa, and to Streptomyces coelicolor hypothetical 11.0 kDa protein SC2E9.05 TR:O54130 (EMBL:AL021530) (98 aa) fasta scores: E(): 4.9e-14, 49.49% id in 99 aa.
  
     0.621
DIP0781
Putative methyltransferase; Similar to Mycobacterium tuberculosis hypothetical tRNA/rRNA methyltransferase Rv0881 or MT0904 or MTCY31.09 SW:Y881_MYCTU (Q10543) (288 aa) fasta scores: E(): 2.5e-52, 53.16% id in 284 aa.
       0.569
DIP1075
Similar to Mycobacterium leprae hypothetical protein ML1706 TR:Q9CBR6 (EMBL:AL583923) (337 aa) fasta scores: E(): 4.5e-19, 32.26% id in 313 aa, and to Mycobacterium tuberculosis CDC1551 vitamin-b12 independent methionine synthase family protein MT3095 TR:AAK47424 (EMBL:AE007129) (337 aa) fasta scores: E(): 1.4e-18, 31.94% id in 313 aa, and to Mycobacterium tuberculosis hypothetical 34.2 kDa protein Rv3015c or MTV012.29C TR:O53262 (EMBL:AL021287) (337 aa) fasta scores: E(): 1.4e-18, 31.94% id in 313 aa.
  
     0.545
rbpA
Conserved hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family.
  
     0.537
whiA
Conserved hypothetical protein; Involved in cell division and chromosome segregation.
  
     0.496
rpoZ
Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
     0.492
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.