STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0780Putative membrane protein; Similar to Streptomyces coelicolor putative integral membrane protein SCD12A.17 TR:Q9KXM3 (EMBL:AL357524) (485 aa) fasta scores: E(): 4.6e-64, 46.04% id in 493 aa. (495 aa)    
Predicted Functional Partners:
DIP2130
Full length similarity to Streptococcus pneumoniae phosphoribosylformylglycinamidine synthase, putative SP0045 TR:AAK74234 (EMBL:AE007322) (1241 aa) fasta scores: E(): 7.8e-167, 47.73% id in 1259 aa. Second two thirds similar to many others e.g. Mycobacterium tuberculosis phosphoribosylformylglycinamidine synthase II PurL or Rv0803 or MT0823 or MTCY07H7A.06c SW:PURL_MYCTU (P54876) (754 aa) fasta scores: E(): 8.3e-22, 26.35% id in 740 aa.
  
  
 0.875
DIP1438
Similar to Escherichia coli O157:H7 uracil transport protein PyrP TR:Q9KX94 (EMBL:AP000422) (442 aa) fasta scores: E(): 5e-46, 45.97% id in 422 aa, and to Escherichia coli uracil permease UraA or B2497 or Z3760 or ECS3359 SW:URAA_ECOLI (P33780) (429 aa) fasta scores: E(): 6.2e-25, 40.9% id in 396 aa.
 
  
 0.744
DIP0781
Putative methyltransferase; Similar to Mycobacterium tuberculosis hypothetical tRNA/rRNA methyltransferase Rv0881 or MT0904 or MTCY31.09 SW:Y881_MYCTU (Q10543) (288 aa) fasta scores: E(): 2.5e-52, 53.16% id in 284 aa.
       0.704
DIP0779
Conserved hypothetical protein; Similar to Mycobacterium leprae hypothetical 28.2 kDa protein ML2142 or MLCB57.29 TR:O33058 (EMBL:Z99494) (269 aa) fasta scores: E(): 5.4e-18, 43.55% id in 225 aa.
       0.642
DIP0777
Putative secreted protein; Similar to Mycobacterium tuberculosis hypothetical 17.8 kDa protein Rv0875c precursor or MT0898 or MTCY31.03c SW:Y875_MYCTU (Q10537) (162 aa) fasta scores: E(): 6e-05, 25.92% id in 162 aa.
       0.571
DIP0778
Putative secreted protein; Similar to Deinococcus radiodurans glutamine cyclotransferase DR0112 TR:Q9RY39 (EMBL:AE001874) (294 aa) fasta scores: E(): 1e-28, 40.84% id in 284 aa.
       0.571
DIP1943
Xanthine/uracil permeases family protein; Similar to Streptomyces coelicolor putative permease SC9G1.04 TR:Q9RKW2 (EMBL:AL132997) (462 aa) fasta scores: E(): 5.6e-61, 41.93% id in 465 aa, and to Escherichia coli putative purine permease YgfU SW:YGFU_ECOLI (Q46821) (482 aa) fasta scores: E(): 9e-55, 38.08% id in 449 aa.
 
  
 0.537
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
  
    0.469
guaA
GMP synthase [glutamine-hydrolysing]; Catalyzes the synthesis of GMP from XMP.
     
 0.462
purK
Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
  
    0.460
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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