STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0788Similar to Streptomyces coelicolor putative oxidoreductase SC4B5.01c TR:Q9ZBW7 (EMBL:AL034443) (277 aa) fasta scores: E(): 1.3e-48, 48% id in 275 aa, and to Corynebacterium sp 2,5-diketo-D-gluconic acid reductase SW:2DKG_CORSP (P15339) (277 aa) fasta scores: E(): 1.1e-39, 44.52% id in 274 aa. (290 aa)    
Predicted Functional Partners:
DIP0789
Putative hydratase; Similar to Mycobacterium leprae probable enoyl-CoA hydratase EchA6 or ML2118 or U650AF SW:ECH6_MYCLE (Q50130) (247 aa) fasta scores: E(): 3.6e-24, 38.86% id in 247 aa, and to Escherichia coli probable enoyl-CoA hydratase PaaF or B1393 SW:PAAF_ECOLI (P76082) (255 aa) fasta scores: E(): 3.3e-13, 34.25% id in 254 aa; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.853
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 0.742
accDA
Similar to Corynebacterium glutamicum putative carboxyltransferase subunit of acetyl-CoA carboxylase AccDA TR:CAC42827 (EMBL:Y17592) (491 aa) fasta scores: E(): 8.9e-58, 55.31% id in 499 aa, and to Escherichia coli acetyl-coenzyme A carboxylase carboxyl transferase subunit beta AccD or DedB or Usg or B2316 or Z3578 or ECS3200 SW:ACCD_ECOLI (P08193) (304 aa) fasta scores: E(): 8.6e-22, 34.89% id in 235 aa.
       0.695
DIP1968
Putative trehalose-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
   
    0.624
etfA
Similar to Mycobacterium tuberculosis electron transfer flavoprotein alpha-subunit EtfA or FixB or Rv3028c or MT3112 or MTV012.43c SW:ETFA_MYCTU (O53275) (318 aa) fasta scores: E(): 1.8e-48, 51.1% id in 317 aa.
     
 0.604
DIP0790
Putative membrane protein; Similar to Streptomyces coelicolor putative integral membrane protein SCI8.08c TR:Q9RJ45 (EMBL:AL132644) (124 aa) fasta scores: E(): 2.6e-18, 43.63% id in 110 aa.
       0.599
DIP0791
Similar to Streptomyces coelicolor putative transmembrane transport protein SCI8.07c TR:Q9RJ46 (EMBL:AL132644) (544 aa) fasta scores: E(): 4.2e-82, 58.31% id in 547 aa; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
       0.599
DIP1090
Putative aldo/keto-reductase family protein; Similar to Escherichia coli ORF_O346 B3001 TR:Q46851 (EMBL:U28377) (346 aa) fasta scores: E(): 2.5e-73, 56.21% id in 354 aa, to Streptomyces coelicolor putative oxidoreductase SC7H9.06 TR:Q9EWJ0 (EMBL:AL450223) (348 aa) fasta scores: E(): 1.6e-65, 58.48% id in 342 aa, and to Homo sapiens voltage-gated potassium channel beta-2 subunit KcnAB2 or KcnA2B or KcnK2 TR:Q13303 (EMBL:U33429) (367 aa) fasta scores: E(): 9.5e-27, 34.74% id in 331 aa.
 
 
0.543
DIP2319
Putative copper zinc superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
   
 
 0.462
DIP2160
Modular polyketide synthase; Similar to Streptomyces verticillus polyketide synthase BlmVIII (bleomycin biosynthesis) TR:Q9FB25 (EMBL:AF210249) (1841 aa) fasta scores: E(): 1.3e-72, 27.240% id in 1931 aa, and to Streptomyces noursei nystatin biosynthesis polyketide synthase Nys TR:Q9L4W3 (EMBL:AF263912) (11096 aa) fasta scores: E(): 4e-71, 33.107% id in 882 aa, and to Amycolatopsis mediterranei rifamycin polyketide synthase TR:Q9F847 (EMBL:AF262754) (1265 aa) fasta scores: E(): 7.7e-61, 31.042% id in 902 aa.
  
 
 0.460
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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