STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0826Putative sulfite synthesis related protein; Similar to Mycobacterium tuberculosis CysQ protein homolog or Rv2131c or MT2189 or MTCY270.37 SW:CYSQ_MYCTU (O06244) (267 aa) fasta scores: E(): 9.2e-23, 52.51% id in 259 aa. (252 aa)    
Predicted Functional Partners:
DIP1475
Conserved hypothetical protein; Similar to, although shorter in its N-terminal region than, Mycobacterium tuberculosis hypothetical 35.4 kDa protein Rv2837c or MTCY16B7.05 TR:P71615 (EMBL:Z81331) (336 aa) fasta scores: E(): 8.5e-29, 34.84% id in 287 aa, and to Clostridium acetobutylicum exopolyphosphatase family protein CAC1804 TR:AAK79769 (EMBL:AE007689) (321 aa) fasta scores: E(): 1.9e-19, 33.19% id in 235 aa.
     
 0.910
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
    0.808
DIP0824
Putative folate reductase; Similar to Mycobacterium avium dihydrofolate reductase FolA TR:O30463 (EMBL:AF006616) (181 aa) fasta scores: E(): 2e-22, 46.1% id in 167 aa, and to Escherichia coli dihydrofolate reductase FolA or TmrA or B0048 SW:DYR_ECOLI (P00379) (159 aa) fasta scores: E(): 1.5e-13, 42.76% id in 152 aa.
     
 0.726
DIP0823
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3292 TR:AAK47635 (EMBL:AE007142) (84 aa) fasta scores: E(): 4.4e-12, 48.1% id in 79 aa.
 
     0.719
DIP0827
Similar to Escherichia coli probable ATP-dependent helicase Lhr or RhlF or B1653 SW:LHR_ECOLI (P30015) (1538 aa) fasta scores: E(): 1.4e-134, 46.42% id in 1579 aa.
       0.709
orn
Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.
      
 0.597
DIP1403
Putative hydrolase; Similar to Mycobacterium tuberculosis inositol-1-monophosphatase SuhB or Rv2701c or MT2775 or MTCY05A6.22c SW:SUHB_MYCTU (O07203) (290 aa) fasta scores: E(): 1e-38, 45% id in 280 aa, and to Escherichia coli inositol-1-monophosphatase SuhB or SsyA or B2533 SW:SUHB_ECOLI (P22783) (267 aa) fasta scores: E(): 3.2e-19, 37.22% id in 231 aa.
 
   
0.582
impA
Similar to Corynebacterium glutamicum inositol monophosphate phosphatase ImpA TR:O52736 (EMBL:AF045998) (259 aa) fasta scores: E(): 3.2e-42, 50.42% id in 236 aa, and to Mycobacterium smegmatis inositol monophosphate phosphatase ImpA TR:O51845 (EMBL:AF005905) (276 aa) fasta scores: E(): 8e-34, 42.35% id in 255 aa.
 
   
 0.520
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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