STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0827Similar to Escherichia coli probable ATP-dependent helicase Lhr or RhlF or B1653 SW:LHR_ECOLI (P30015) (1538 aa) fasta scores: E(): 1.4e-134, 46.42% id in 1579 aa. (1604 aa)    
Predicted Functional Partners:
DIP0829
Putative endonuclease; Similar to Streptomyces coelicolor putative endonuclease VIII Nei or SC7C7.15c SW:END8_STRCO (O86820) (276 aa) fasta scores: E(): 2.5e-39, 40.87% id in 274 aa, and to Escherichia coli endonuclease VIII Nei or B0714 SW:END8_ECOLI (P50465) (262 aa) fasta scores: E(): 4.6e-14, 28.88% id in 277 aa.
 
  
 0.900
DIP0826
Putative sulfite synthesis related protein; Similar to Mycobacterium tuberculosis CysQ protein homolog or Rv2131c or MT2189 or MTCY270.37 SW:CYSQ_MYCTU (O06244) (267 aa) fasta scores: E(): 9.2e-23, 52.51% id in 259 aa.
       0.709
radA
Conserved hypothetical protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
   
    0.661
rpsA
30S ribosomal protein S1; Similar to Corynebacterium ammoniagenes 30s ribosomal protein S1 RpsA SWALL:Q9LBD0 (EMBL:AF045481) (489 aa) fasta scores: E(): 6e-160, 92.18% id in 486 aa, and to Escherichia coli 30S ribosomal protein S1 RpsA or SsyF or B0911 or Z1257 or ECS0994 SWALL:RS1_ECOLI (SWALL:P02349) (557 aa) fasta scores: E(): 2.9e-52, 44.97% id in 358 aa.
  
   
 0.658
DIP0752
IS element transposase; Similar to Escherichia coli possible transposase of IS1353 YahA TR:Q9WTH9 (EMBL:AP000342) (514 aa) fasta scores: E(): 2.6e-62, 41.595% id in 464 aa, and to Escherichia coli putative transposase InsK for insertion sequence element IS150 or B3558 SW:INSK_ECOLI (P19769) (283 aa) fasta scores: E(): 2.7e-35, 38.628% id in 277 aa.
      
 0.617
DIP1266
Putative transposase; Similar to, although shorter in its N-terminal region than Escherichia coli possible transposase of IS1353 YahA SWALL:Q9WTH9 (EMBL:AP000342) (514 aa) fasta scores: E(): 2.5e-62, 41.59% id in 464 aa, and similar to, although longer in its N-terminal region than Escherichia coli putative transposase InsK for insertion sequence element IS150 or B3558 SWALL:INSK_ECOLI (SWALL:P19769) (283 aa) fasta scores: E(): 2.6e-35, 38.62% id in 277 aa.
      
 0.617
DIP1366
Putative transposase; Similar to, although shorter than Escherichia coli possible transposase of IS1353 YahA SWALL:Q9WTH9 (EMBL:AP000342) (514 aa) fasta scores: E(): 1.4e-62, 41.59% id in 464 aa, and similar in its C-terminal region to Escherichia coli putative transposase InsK for insertion sequence element IS150 InsK or B3558 SWALL:INSK_ECOLI (SWALL:P19769) (283 aa) fasta scores: E(): 1.4e-35, 38.98% id in 277 aa.
      
 0.614
DIP1423
Similar to Escherichia coli ATP-dependent helicase HrpA or B1413 SW:HRPA_ECOLI (P43329) (1300 aa) fasta scores: E(): 1.7e-172, 46.92% id in 1315 aa, and to Vibrio cholerae ATP-dependent helicase HrpA VC1382 TR:Q9KS77 (EMBL:AE004217) (1309 aa) fasta scores: E(): 2.3e-171, 47.6% id in 1317 aa.
      
 0.614
DIP0824
Putative folate reductase; Similar to Mycobacterium avium dihydrofolate reductase FolA TR:O30463 (EMBL:AF006616) (181 aa) fasta scores: E(): 2e-22, 46.1% id in 167 aa, and to Escherichia coli dihydrofolate reductase FolA or TmrA or B0048 SW:DYR_ECOLI (P00379) (159 aa) fasta scores: E(): 1.5e-13, 42.76% id in 152 aa.
       0.606
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.606
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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