STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpmB2Similar to Mycobacterium tuberculosis 50S ribosomal protein L28-2 RpmB2 or Rv2058c or MT2118 or MTCY63A.02 SW:R28B_MYCTU (O86357) (78 aa) fasta scores: E(): 7.7e-22, 70.51% id in 78 aa; Belongs to the bacterial ribosomal protein bL28 family. (78 aa)    
Predicted Functional Partners:
rpmG
Similar to Mycobacterium tuberculosis 50S ribosomal protein L33 type 1 RpmG1 or RpmG or Rv2057c or MT2117.1 or MTCY63A.03 SW:R331_MYCTU (O86356) (54 aa) fasta scores: E(): 7e-18, 75.92% id in 54 aa; Belongs to the bacterial ribosomal protein bL33 family.
 
 
 0.999
rpsR2
30S ribosomal protein S18-2; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
 
 
 0.998
rpsN
30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.
 
 
 0.998
rplI
50S ribosomal protein L9; Binds to the 23S rRNA.
  
 
 0.996
rpmE
Similar to Streptomyces coelicolor 50S ribosomal protein L31 type B-2 RpmE3 or SCE9.34c TR:Q9X8K6 (EMBL:AL049841) (84 aa) fasta scores: E(): 1.4e-18, 60.75% id in 79 aa.
 
 
 0.993
rpmF
Similar to Mycobacterium leprae 50S ribosomal protein L32 RpmF or ML0173 SW:RL32_MYCLE (Q9CD69) (57 aa) fasta scores: E(): 4e-11, 57.14% id in 56 aa; Belongs to the bacterial ribosomal protein bL32 family.
 
 
 0.993
rpmJ
50S ribosomal protein L36; Similar to Bacillus stearothermophilus 50S ribosomal protein L36 RpmJ SW:RL36_BACST (P07841) (37 aa) fasta scores: E(): 0.0052, 50% id in 40 aa, and to Streptomyces coelicolor putative ribosomal protein L36 SC8B3.03c TR:CAC44182 (EMBL:AL593822) (40 aa) fasta scores: E(): 2.3e-12, 85% id in 40 aa.
  
 
 0.990
rpmA
Similar to Escherichia coli 50S ribosomal protein L27 RpmA SW:RL27_ECOLI (P02427) (84 aa) fasta scores: E(): 3.1e-16, 64.19% id in 81 aa, and to Mycobacterium leprae 50S ribosomal protein L27 ML1466 SW:RL27_MYCLE (Q9CBZ3) (88 aa) fasta scores: E(): 2.7e-24, 83.95% id in 81 aa; Belongs to the bacterial ribosomal protein bL27 family.
  
 
 0.980
rplE
50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
   
 
 0.978
rpsO
30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
  
 
 0.978
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.