STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0856Putative serine protease; Similar to Mycobacterium tuberculosis putative serine protease Rv0983 or MTV044.11 SWALL:O53896 (EMBL:AL021999) (464 aa) fasta scores: E(): 3.8e-46, 43.84% id in 406 aa, and to Brucella abortus probable serine protease do-like precursor DegP or HtrA SWALL:DEGP_BRUAB (SWALL:Q44597) (513 aa) fasta scores: E(): 7.6e-25, 44.56% id in 285 aa. (428 aa)    
Predicted Functional Partners:
DIP0857
Similar to Mycobacterium leprae putative molybdenum cofactor biosynthesis protein MoaB or ML0177 or MLCB373.29 TR:Q9Z5G5 (EMBL:AL035500) (181 aa) fasta scores: E(): 8.3e-28, 60% id in 150 aa.
  
    0.934
arc
Putative AAA protein family ATPase; Similar to, although shorter in its N-terminal region than Streptomyces coelicolor AAA protein family ATPase Arc SWALL:Q9RJ58 (EMBL:AL132648) (588 aa) fasta scores: E(): 3e-76, 54.14% id in 519 aa, and to, although shorter in its N-terminal region than Mycobacterium leprae putative AAA-family ATPase ML1316 or MLCB2533.12 or A2126A or B2126_C1_167 SWALL:YL15_MYCLE (SWALL:P46509) (609 aa) fasta scores: E(): 2.1e-58, 54.99% id in 531 aa.
    
 0.807
DIP0855
Putative two component system sensor kinase; Similar to Corynebacterium glutamicum sensor kinase TR:Q9F160 (EMBL:AF119221) (455 aa) fasta scores: E(): 6.5e-71, 46.98% id in 447 aa, and to Burkholderia pseudomallei sensor protein IrlS SW:IRLS_BURPS (O31396) (464 aa) fasta scores: E(): 4.6e-18, 26% id in 446 aa.
    
 0.713
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.644
DIP0854
Putative two component system response regulator; Similar to Corynebacterium glutamicum response regulator TR:Q9F161 (EMBL:AF119221) (232 aa) fasta scores: E(): 2.4e-67, 79.31% id in 232 aa, and to Pseudomonas syringae transcriptional activator protein CopR SW:COPR_PSESM (Q02540) (227 aa) fasta scores: E(): 1.9e-32, 48% id in 225 aa.
  
  
 0.631
clpP1
ATP-dependent Clp protease proteolytic subunit 1; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
  
  
 0.584
rpmF
Similar to Mycobacterium leprae 50S ribosomal protein L32 RpmF or ML0173 SW:RL32_MYCLE (Q9CD69) (57 aa) fasta scores: E(): 4e-11, 57.14% id in 56 aa; Belongs to the bacterial ribosomal protein bL32 family.
  
 
 0.566
DIP0858
Hypothetical protein; Doubtful CDS. No strong consensus RBS usptream. No significant database matches.
       0.566
dtxR
Diphtheria toxin repressor; Iron-binding repressor of the dipheteria toxin gene expression. May serve as a global regulator of gene expression. Represses ripA under iron excess.
   
    0.563
DIP2245
Similar to Mycobacterium leprae putative phosphoglycerate mutase ML0079 TR:Q9CDC3 (EMBL:AL583917) (231 aa) fasta scores: E(): 4e-11, 33.64% id in 214 aa, and to Schizosaccharomyces pombe phosphoglycerate mutase Gpm1 or SPAC26F1.06 SW:PMGY_SCHPO (P36623) (211 aa) fasta scores: E(): 0.28, 24.4% id in 209 aa.
   
    0.563
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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