STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DIP0861Conserved hypothetical protein; Similar to Mycobacterium leprae hypothetical 21.3 kDa protein ML0181 or MLCB373.33c TR:Q9Z5G2 (EMBL:AL035500) (197 aa) fasta scores: E(): 2.1e-14, 34.73% id in 190 aa; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (194 aa)    
Predicted Functional Partners:
folD
Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.915
purN
5'-phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
    
 0.906
DIP0860
Putative membrane protein; No significant database matches.
       0.815
DIP0862
Putative urydyltransferase; Similar to Mycobacterium tuberculosis CDC1551 UTP--glucose-1-phosphate uridylyltransferase MT1022 TR:AAK45269 (EMBL:AE006986) (306 aa) fasta scores: E(): 3.2e-65, 64.8% id in 287 aa, and to Bacillus subtilis UTP--glucose-1-phosphate uridylyltransferase GtaB SW:GTAB_BACSU (Q05852) (292 aa) fasta scores: E(): 1.4e-32, 40.67% id in 295 aa.
     
 0.700
mscL
Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
       0.652
pheT
Similar to Mycobacterium tuberculosis phenylalanyl-tRNA synthetase beta chain PheT or Rv1650 or MT1688 or MTCY06H11.15 SWALL:SYFB_MYCTU (SWALL:P94985) (831 aa) fasta scores: E(): 4.2e-156, 49.64% id in 844 aa, and to Bacillus subtilis phenylalanyl-tRNA synthetase beta chain PheT SWALL:SYFB_BACSU (SWALL:P17922) (804 aa) fasta scores: E(): 1.8e-53, 30.69% id in 847 aa.
 
  
 0.606
DIP0863
Putative molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
       0.572
DIP0864
Putative acetyltransferase; Similar to Mycobacterium leprae possible acetyltransferase RimJ or ML0184 TR:Q9CD65 (EMBL:AL583917) (214 aa) fasta scores: E(): 3.6e-35, 47.03% id in 202 aa.
  
    0.551
DIP0865
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 39.5 kDa protein Rv0996 or MTCI237.10 TR:O05579 (EMBL:Z94752) (358 aa) fasta scores: E(): 1.8e-13, 30.27% id in 370 aa.
       0.482
DIP0027
Putative membrane protein; Similar to Mycobacterium tuberculosis putative transmembrane protein Rv0110 or MTV031.04 TR:O53632 (EMBL:AL021926) (249 aa) fasta scores: E(): 1.4e-13, 34.19% id in 193 aa.
  
  
 0.410
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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