STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0874Putative secreted protein; Similar to Mycobacterium tuberculosis hypothetical 38.1 kDa protein Rv1009 or MTCI237.26 TR:O05594 (EMBL:Z94752) (362 aa) fasta scores: E(): 1.8e-39, 38.71% id in 372 aa. (385 aa)    
Predicted Functional Partners:
rsmA
Putative dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
  
  
 0.963
ispE
Putative kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
     
 0.803
DIP0873
Conserved hypothetical protein; Similar to Corynebacterium glutamicum Mg-dependent DNAse CGL0908 SWALL:Q8NRY3 (EMBL:AP005276) (277 aa) fasta scores: E(): 3.7e-81, 73.74% id in 278 aa, and to Mycobacterium tuberculosis hypothetical protein Ycfh Rv1008 or MTCI237.25 TR:O08343 (EMBL:Z94752) (264 aa) fasta scores: E(): 4.4e-40, 44.61% id in 260 aa.
     
 0.766
DIP0877
Similar to Streptomyces coelicolor putative ABC transporter ATP-binding subunit SCE66.26c TR:Q9K3R7 (EMBL:AL359989) (604 aa) fasta scores: E(): 2.3e-97, 54.75% id in 610 aa.
     
 0.749
DIP0878
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 12.0 kDa protein Rv1117 or MTCY22G8.06 TR:O06569 (EMBL:Z95585) (107 aa) fasta scores: E(): 3.6e-13, 43.92% id in 107 aa.
       0.699
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
       0.614
ctaC
Putative cytochrome C oxidase precursor; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity).
      
 0.574
rsmI
Conserved hypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
       0.570
DIP1281
Putative invasion protein; Similar to Mycobacterium tuberculosis hypothetical 49.8 kDa protein Rv1477 or MT1524 or MTV007.24 SWALL:O53168 (EMBL:AL021184) (472 aa) fasta scores: E(): 3.5e-21, 31.88% id in 577 aa, and C-terminal half similar to the whole length of Mycobacterium tuberculosis hypothetical invasion protein Inv1 SWALL:O33171 (EMBL:AF006054) (277 aa) fasta scores: E(): 1e-17, 39.5% id in 281 aa. Note: Contains two possible colied-coil region at residues 102..130 and 182..360.
  
  
 0.568
DIP0882
Similar to Mycobacterium tuberculosis CDC1551 RNA polymerase sigma factor, putative MT3329 TR:AAK47672 (EMBL:AE007144) (295 aa) fasta scores: E(): 1.4e-68, 61.42% id in 280 aa, and to Pseudomonas aeruginosa pao substrain OT684 pyoverdine gene transcriptional regulator PvdS TR:P72119 (EMBL:U12891) (237 aa) fasta scores: E(): 5.9e-56, 59.91% id in 237 aa.
       0.532
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.