Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DIP0882Similar to Mycobacterium tuberculosis CDC1551 RNA polymerase sigma factor, putative MT3329 TR:AAK47672 (EMBL:AE007144) (295 aa) fasta scores: E(): 1.4e-68, 61.42% id in 280 aa, and to Pseudomonas aeruginosa pao substrain OT684 pyoverdine gene transcriptional regulator PvdS TR:P72119 (EMBL:U12891) (237 aa) fasta scores: E(): 5.9e-56, 59.91% id in 237 aa. (301 aa)    
Predicted Functional Partners:
DIP2016
Similar to Pseudomonas aeruginosa hypothetical protein PA0141 SWALL:Q9I6Z1 (EMBL:AE004452) (298 aa) fasta scores: E(): 1.2e-69, 62.06% id in 261 aa, and to Rhizobium loti MLL5641 protein SWALL:Q98BC2 (EMBL:AP003007) (302 aa) fasta scores: E(): 9.2e-57, 49.63% id in 274 aa.
  
  
 
0.906
DIP0881
Hypothetical protein; No significant database matches.
       0.674
DIP0880
Similar to Xanthomonas campestris probable RNA polymerase sigma factor RfaY SW:RFAY_XANCP (P46358) (217 aa) fasta scores: E(): 9.8e-07, 32.88% id in 149 aa; Belongs to the sigma-70 factor family. ECF subfamily.
       0.656
DIP0878
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 12.0 kDa protein Rv1117 or MTCY22G8.06 TR:O06569 (EMBL:Z95585) (107 aa) fasta scores: E(): 3.6e-13, 43.92% id in 107 aa.
       0.591
DIP0879
Putative membrane protein; No significant database matches.
       0.591
rsmA
Putative dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
       0.575
ispE
Putative kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
       0.575
DIP0877
Similar to Streptomyces coelicolor putative ABC transporter ATP-binding subunit SCE66.26c TR:Q9K3R7 (EMBL:AL359989) (604 aa) fasta scores: E(): 2.3e-97, 54.75% id in 610 aa.
       0.575
DIP0874
Putative secreted protein; Similar to Mycobacterium tuberculosis hypothetical 38.1 kDa protein Rv1009 or MTCI237.26 TR:O05594 (EMBL:Z94752) (362 aa) fasta scores: E(): 1.8e-39, 38.71% id in 372 aa.
       0.532
rsmI
Conserved hypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
     
 0.480
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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