STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0896Putative oxydoreductase; Similar to Streptomyces peucetius daunorubicin C-13 ketoreductase DnrU TR:Q9ZAU1 (EMBL:U77891) (287 aa) fasta scores: E(): 1.3e-16, 35.25% id in 278 aa. (269 aa)    
Predicted Functional Partners:
fas
Putative fatty acid synthase; Similar to the N-terminal region of Corynebacterium ammoniagenes fatty acid synthase Fas TR:Q04846 (EMBL:X64795) (3104 aa) fasta scores: E(): 0, 61.33% id in 3018 aa, and to the full length of Mycobacterium tuberculosis fatty acid synthase Rv2524c TR:AAK46907 (EMBL:Z83863) (3069 aa) fasta scores: E(): 1e-197, 51.37% id in 3083 aa, and of Corynebacterium glutamicum 3-oxoacyl-(acyl-carrier-protein) synthase CGL2495 SWALL:Q8NMS0 (EMBL:AP005281) (2993 aa) fasta scores: E(): 0, 67.35% id in 3008 aa.
  
 0.966
prfC
Putative peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
       0.762
DIP2189
Putative polyketide synthase; Similar to Mycobacterium tuberculosis polyketide synthase PKS13 or Rv3800c or MTV026.05c TR:O53579 (EMBL:AL022076) (1733 aa) fasta scores: E(): 5.4e-109, 44.5% id in 1719 aa, and to Polyangium cellulosum soraphen polyketide synthase A SorA TR:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 6.2e-101, 35.96% id in 1090 aa.
  
 
 0.740
uvrD
Putative DNA helicase II; Similar to Mycobacterium tuberculosis probable DNA helicase II homolog UvrD or Rv3198c or MT3291 or MTV014.42c SW:UVRD_MYCTU (O53344) (700 aa) fasta scores: E(): 2.7e-133, 58.92% id in 689 aa, and to Escherichia coli DNA helicase II UvrD or MutU or PdeB or Rad or RecL or B3813 SW:UVRD_ECOLI (P03018) (720 aa) fasta scores: E(): 7.8e-37, 32.16% id in 656 aa.
    
 
 0.721
pth
Putative peptidyl tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
       0.675
DIP1025
Putative exonuclease, SbcD-family; Similar to Mycobacterium tuberculosis CDC1551 exonuclease SbcD-related protein MT1314 TR:AAK45575 (EMBL:AE007006) (417 aa) fasta scores: E(): 3e-43, 40.1% id in 384 aa, and to Bacillus subtilis exonuclease SbcD homolog SW:SBCD_BACSU (P23479) (325 aa) fasta scores: E(): 1.6, 27.13% id in 258 aa.
    
   0.635
DIP1768
Conserved hypothetical protein; Similar to Streptomyces coelicolor putative ankyrin-like protein SC6D7.25 TR:Q9RKX3 (EMBL:AL133213) (134 aa) fasta scores: E(): 4.4e-23, 57.36% id in 129 aa, and to Campylobacter jejuni ankyrin-repeat containing protein Cj1386 TR:Q9PMR4 (EMBL:AL139078) (156 aa) fasta scores: E(): 1.2e-10, 39.66% id in 121 aa.
   
 0.618
accDA
Similar to Corynebacterium glutamicum putative carboxyltransferase subunit of acetyl-CoA carboxylase AccDA TR:CAC42827 (EMBL:Y17592) (491 aa) fasta scores: E(): 8.9e-58, 55.31% id in 499 aa, and to Escherichia coli acetyl-coenzyme A carboxylase carboxyl transferase subunit beta AccD or DedB or Usg or B2316 or Z3578 or ECS3200 SW:ACCD_ECOLI (P08193) (304 aa) fasta scores: E(): 8.6e-22, 34.89% id in 235 aa.
  
  
 0.578
DIP2161
Nonribosomal peptide synthase; Similar to Stigmatella aurantiaca myxothiazol synthase MtaC TR:Q9RFK9 (EMBL:AF188287) (1290 aa) fasta scores: E(): 1.7e-86, 35.694% id in 1073 aa, and to Polyangium cellulosum epothilone biosynthase EpoB TR:Q9KIZ9 (EMBL:AF217189) (1410 aa) fasta scores: E(): 1.8e-81, 35.385% id in 975 aa, and to Pseudomonas aeruginosa pyochelin synthetase PchF or PA4225 TR:Q9HWG4 (EMBL:AE004839) (1809 aa) fasta scores: E(): 1.9e-81, 37.017% id in 932 aa.
  
 
 0.573
DIP2160
Modular polyketide synthase; Similar to Streptomyces verticillus polyketide synthase BlmVIII (bleomycin biosynthesis) TR:Q9FB25 (EMBL:AF210249) (1841 aa) fasta scores: E(): 1.3e-72, 27.240% id in 1931 aa, and to Streptomyces noursei nystatin biosynthesis polyketide synthase Nys TR:Q9L4W3 (EMBL:AF263912) (11096 aa) fasta scores: E(): 4e-71, 33.107% id in 882 aa, and to Amycolatopsis mediterranei rifamycin polyketide synthase TR:Q9F847 (EMBL:AF262754) (1265 aa) fasta scores: E(): 7.7e-61, 31.042% id in 902 aa.
 
 
 0.570
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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