STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0907Putative reductase; Similar to Corynebacterium glutamicum hypothetical 33.0 kDa protein in proB-proA intergenic region SW:YPRA_CORGL (P45637) (304 aa) fasta scores: E(): 7.5e-48, 45.3% id in 309 aa, and to Escherichia coli 2-ketogluconate reductase TkrA or B3553 SW:TKRA_ECOLI (P37666) (324 aa) fasta scores: E(): 1.4e-13, 31.57% id in 247 aa. (309 aa)    
Predicted Functional Partners:
DIP0398
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 32.7 kDa protein Rv0505c or MT0526 or MTCY20G9.32c SW:Y505_MYCTU (Q11169) (308 aa) fasta scores: E(): 4.7e-52, 59.67% id in 243 aa.
  
 
 0.855
DIP0784
Putative phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
  
 
 0.799
DIP0908
Putative ABC transport system membrane protein; Similar to Corynebacterium striatum ABC transporter TetA TR:Q9Z4Q1 (EMBL:U21300) (513 aa) fasta scores: E(): 1.3e-45, 33.98% id in 509 aa.
 
 
   0.750
DIP0909
Putative ABC transport system ATP-binding protein; Similar to C-terminal region of Mycobacterium smegmatis ExiT TR:O85018 (EMBL:AF034152) (1122 aa) fasta scores: E(): 5.9e-45, 34.56% id in 596 aa, and to Streptomyces coelicolor putative ABC-transporter transmembrane protein SCF34.12c TR:Q9RK13 (EMBL:AL109974) (601 aa) fasta scores: E(): 1.5e-42, 33.98% id in 612 aa.
   
   0.708
DIP0906
Putative membrane protein; Low similarity to Streptomyces coelicolor putative integral membrane protein SCI35.39 TR:O88074 (EMBL:AL031541) (394 aa) fasta scores: E(): 1.8e-16, 29.34% id in 351 aa.
       0.693
rpmA
Similar to Escherichia coli 50S ribosomal protein L27 RpmA SW:RL27_ECOLI (P02427) (84 aa) fasta scores: E(): 3.1e-16, 64.19% id in 81 aa, and to Mycobacterium leprae 50S ribosomal protein L27 ML1466 SW:RL27_MYCLE (Q9CBZ3) (88 aa) fasta scores: E(): 2.7e-24, 83.95% id in 81 aa; Belongs to the bacterial ribosomal protein bL27 family.
   
   0.624
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
   0.624
DIP0311
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 30.7 kDa protein Rv3661 or MT3761 or MTV025.009 SW:Y0G1_MYCTU (O69629) (287 aa) fasta scores: E(): 2.2e-40, 45.22% id in 272 aa, and to Streptomyces coelicolor putative morphological differentiation-associated protein SCH5.21 TR:Q9X923 (EMBL:AL035636) (268 aa) fasta scores: E(): 5e-38, 45.8% id in 262 aa.
  
 
 0.623
rplF
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
   0.585
rplB
50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
    
   0.502
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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