STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0910Similar to Mycobacterium tuberculosis CDC1551 transcriptional regulator, tetR family MT1047 TR:AAK45298 (EMBL:AE006987) (202 aa) fasta scores: E(): 4.4e-45, 63.9% id in 205 aa. (215 aa)    
Predicted Functional Partners:
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
     
 0.797
DIP0915
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 35.4 kDa protein Rv1021 or MTCY10G2.28c TR:P96379 (EMBL:Z92539) (325 aa) fasta scores: E(): 3.2e-20, 38.61% id in 202 aa.
     
 0.501
prsA
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
    0.489
glmU
Putative UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family.
       0.486
DIP0912
Hypothetical protein; No significant database matches.
       0.483
DIP0913
Hypothetical protein; No significant database matches.
       0.483
DIP1412
Conserved hypothetical protein; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality.
  
     0.460
DIP1384
Similar to Streptomyces coelicolor putative sugar transferase SCL2.15c SWALL:Q9L284 (EMBL:AL137778) (387 aa) fasta scores: E(): 3.5e-45, 49.06% id in 375 aa, and to Mycobacterium tuberculosis CDC1551 glycosyl transferase MT2685 SWALL:AAK47001 (EMBL:AE007101) (378 aa) fasta scores: E(): 9.2e-42, 47.89% id in 380 aa.
  
     0.427
DIP0908
Putative ABC transport system membrane protein; Similar to Corynebacterium striatum ABC transporter TetA TR:Q9Z4Q1 (EMBL:U21300) (513 aa) fasta scores: E(): 1.3e-45, 33.98% id in 509 aa.
       0.414
DIP0909
Putative ABC transport system ATP-binding protein; Similar to C-terminal region of Mycobacterium smegmatis ExiT TR:O85018 (EMBL:AF034152) (1122 aa) fasta scores: E(): 5.9e-45, 34.56% id in 596 aa, and to Streptomyces coelicolor putative ABC-transporter transmembrane protein SCF34.12c TR:Q9RK13 (EMBL:AL109974) (601 aa) fasta scores: E(): 1.5e-42, 33.98% id in 612 aa.
       0.414
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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