STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lysIL-Lysine transport protein; Similar to Corynebacterium glutamicum L-Lysine transport protein LysI SW:LYSI_CORGL (P35865) (501 aa) fasta scores: E(): 9.3e-131, 69.85% id in 491 aa. (498 aa)    
Predicted Functional Partners:
brnQ
Branched-chain amino acid ABC transport system membrane protein; Component of the transport system for branched-chain amino acids.
 
   
 0.724
DIP0947
Putative sodium-dependent ABC transport system membrane protein; Similar to Pasteurella multocida hypothetical protein PM0718 TR:Q9CMU0 (EMBL:AE006109) (502 aa) fasta scores: E(): 6.7e-106, 57.72% id in 492 aa, and to Haemophilus influenzae hypothetical sodium-dependent transporter HI0736 SW:Y736_HAEIN (P44849) (508 aa) fasta scores: E(): 2.9e-104, 55.17% id in 502 aa; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
  
 
 0.695
DIP0915
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 35.4 kDa protein Rv1021 or MTCY10G2.28c TR:P96379 (EMBL:Z92539) (325 aa) fasta scores: E(): 3.2e-20, 38.61% id in 202 aa.
       0.683
DIP0916
Putative secreted protein; Similar to Mycobacterium tuberculosis hypothetical 25.8 kDa protein LpqU or Rv1022 or MTCY10G2.27c TR:P96378 (EMBL:Z92539) (243 aa) fasta scores: E(): 7.2e-34, 46.02% id in 239 aa.
       0.673
putP
Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
   
  
 0.648
ptsG
Similar to Corynebacterium glutamicum PTS system, glucose-specific IIABC component PtsG SWALL:PTGA_CORGL (SWALL:Q45298) (674 aa) fasta scores: E(): 2.8e-59, 44.91% id in 688 aa, and to Staphylococcus xylosus PTS system, sucrose-specific IIBC component ScrA SWALL:PTSB_STAXY (SWALL:P51184) (480 aa) fasta scores: E(): 8e-26, 27.73% id in 494 aa.
      
 0.535
argD
Similar to Corynebacterium glutamicum acetylornithine aminotransferase ArgD SWALL:ARGD_CORGL (SWALL:Q59282) (389 aa) fasta scores: E(): 2.9e-98, 65.21% id in 391 aa, and to Mycobacterium tuberculosis acetylornithine aminotransferase ArgD or Rv1655 or MT1693 or MTCY06H11.20 SWALL:ARGD_MYCTU (SWALL:P94990) (400 aa) fasta scores: E(): 5.2e-74, 50.12% id in 405 aa; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
 
 
 0.530
sdaC
Similar to Escherichia coli serine transporter SdaC or DcrA or B2796 or Z4113 or ECS3656 SW:SDAC_ECOLI (P36559) (429 aa) fasta scores: E(): 4.6e-100, 61.66% id in 420 aa.
  
 
 
 0.507
trpC1
Similar to Corynebacterium glutamicum tryptophan biosynthesis protein TrpCF [includes: indole-3-glycerol phosphate synthase trpC SW:TRPC_CORGL (P06560) (474 aa) fasta scores: E(): 7.5e-121, 70.15% id in 459 aa, and to Escherichia coli tryptophan biosynthesis protein TrpCF [includes: indole-3-glycerol phosphate synthase TrpC or b1262 SW:TRPC_ECOLI (P00909) (452 aa) fasta scores: E(): 3.9e-58, 41.7% id in 482 aa. Note overlap with upstream gene suggesting possible downstream translational start codon; Belongs to the TrpF family.
    
 
 0.507
DIP0357
C-terminal region Similar to Deinococcus radiodurans alpha-dextran endo-1,6-alpha-glucosidase DR0405 TR:Q9RXB0 (EMBL:AE001900) (910 aa) fasta scores: E(): 3.1e-110, 41.4% id in 942 aa, and N-terminal region similar to Streptomyces lividans alpha-amylase precursor Amy SW:AMY_STRLI (Q05884) (919 aa) fasta scores: E(): 1.4e-86, 41.56% id in 676 aa; Belongs to the glycosyl hydrolase 13 family.
  
 0.479
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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