Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
DIP0915Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 35.4 kDa protein Rv1021 or MTCY10G2.28c TR:P96379 (EMBL:Z92539) (325 aa) fasta scores: E(): 3.2e-20, 38.61% id in 202 aa. (232 aa)    
Predicted Functional Partners:
DIP0916
Putative secreted protein; Similar to Mycobacterium tuberculosis hypothetical 25.8 kDa protein LpqU or Rv1022 or MTCY10G2.27c TR:P96378 (EMBL:Z92539) (243 aa) fasta scores: E(): 7.2e-34, 46.02% id in 239 aa.
       0.822
lysI
L-Lysine transport protein; Similar to Corynebacterium glutamicum L-Lysine transport protein LysI SW:LYSI_CORGL (P35865) (501 aa) fasta scores: E(): 9.3e-131, 69.85% id in 491 aa.
       0.683
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
       0.622
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
     
 0.564
DIP0918
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 24.6 kDa protein Rv1024 or MTCY10G2.25c TR:P96376 (EMBL:Z92539) (228 aa) fasta scores: E(): 1.5e-08, 31.21% id in 157 aa.
       0.529
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
      
 0.528
DIP0920
Conserved hypothetical protein; Similar to Mycobacterium leprae hypothetical 33.5 kDa protein ML0258 or MLCB4.02 TR:O69585 (EMBL:AL023514) (317 aa) fasta scores: E(): 9e-53, 52.56% id in 312 aa.
       0.480
DIP0919
Similar to Mycobacterium leprae hypothetical protein ML0257 TR:Q9CD40 (EMBL:AL583917) (167 aa) fasta scores: E(): 4e-33, 59.49% id in 158 aa.
       0.471
DIP1790
Glutamine amidotransferase protein; N-terminal region is similar to Streptomyces griseus para-aminobenzoate synthase Pab SW:PABS_STRGR (P32483) (723 aa) fasta scores: E(): 1.8e-48, 39.11% id in 698 aa, and to Streptomyces pristinaespiralis p-aminobenzoate synthase PapA TR:P72539 (EMBL:U60417) (719 aa) fasta scores: E(): 6.1e-43, 35.83% id in 734 aa.
     
 0.465
pheT
Similar to Mycobacterium tuberculosis phenylalanyl-tRNA synthetase beta chain PheT or Rv1650 or MT1688 or MTCY06H11.15 SWALL:SYFB_MYCTU (SWALL:P94985) (831 aa) fasta scores: E(): 4.2e-156, 49.64% id in 844 aa, and to Bacillus subtilis phenylalanyl-tRNA synthetase beta chain PheT SWALL:SYFB_BACSU (SWALL:P17922) (804 aa) fasta scores: E(): 1.8e-53, 30.69% id in 847 aa.
 
   
 0.452
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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