STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0915Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 35.4 kDa protein Rv1021 or MTCY10G2.28c TR:P96379 (EMBL:Z92539) (325 aa) fasta scores: E(): 3.2e-20, 38.61% id in 202 aa. (232 aa)    
Predicted Functional Partners:
DIP0916
Putative secreted protein; Similar to Mycobacterium tuberculosis hypothetical 25.8 kDa protein LpqU or Rv1022 or MTCY10G2.27c TR:P96378 (EMBL:Z92539) (243 aa) fasta scores: E(): 7.2e-34, 46.02% id in 239 aa.
       0.828
lysI
L-Lysine transport protein; Similar to Corynebacterium glutamicum L-Lysine transport protein LysI SW:LYSI_CORGL (P35865) (501 aa) fasta scores: E(): 9.3e-131, 69.85% id in 491 aa.
       0.698
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
       0.640
era
Putative GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
   
 
 0.552
DIP0918
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 24.6 kDa protein Rv1024 or MTCY10G2.25c TR:P96376 (EMBL:Z92539) (228 aa) fasta scores: E(): 1.5e-08, 31.21% id in 157 aa.
       0.550
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
     
 0.504
DIP0910
Similar to Mycobacterium tuberculosis CDC1551 transcriptional regulator, tetR family MT1047 TR:AAK45298 (EMBL:AE006987) (202 aa) fasta scores: E(): 4.4e-45, 63.9% id in 205 aa.
     
 0.501
DIP0920
Conserved hypothetical protein; Similar to Mycobacterium leprae hypothetical 33.5 kDa protein ML0258 or MLCB4.02 TR:O69585 (EMBL:AL023514) (317 aa) fasta scores: E(): 9e-53, 52.56% id in 312 aa.
       0.495
DIP0919
Similar to Mycobacterium leprae hypothetical protein ML0257 TR:Q9CD40 (EMBL:AL583917) (167 aa) fasta scores: E(): 4e-33, 59.49% id in 158 aa.
       0.481
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
      
 0.443
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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