STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0923Putative membrane protein; Similar to Mycobacterium tuberculosis putative transmembrane protein Rv1072 or MTV017.25 TR:O53420 (EMBL:AL021897) (278 aa) fasta scores: E(): 2.4e-47, 58.21% id in 280 aa. (276 aa)    
Predicted Functional Partners:
ripA
Putative araC-family transcriptional regulator; Under iron limitation, represses the acn (aconitase), catA (catechol 1,2 dioxygenase), leuCD (isopropylmalate dehydratase), narKGHJI (nitrite/nitrate transporter and nitrate reductase), sdhCAB (succinate dehydrogenase), pta (phosphotransacetylase) and katA (catalase) genes.
       0.524
DIP0919
Similar to Mycobacterium leprae hypothetical protein ML0257 TR:Q9CD40 (EMBL:AL583917) (167 aa) fasta scores: E(): 4e-33, 59.49% id in 158 aa.
 
     0.443
DIP1000
Similar to Mycobacterium tuberculosis hypothetical 18.6 kDa protein Rv1234 or MTV006.06 TR:O50451 (EMBL:AL021006) (175 aa) fasta scores: E(): 2.9e-27, 56.42% id in 140 aa.
  
    0.404
DIP1952
Similar to Escherichia coli pyruvate dehydrogenase [cytochrome] PoxB SW:POXB_ECOLI (P07003) (572 aa) fasta scores: E(): 1.2e-100, 45.89% id in 573 aa, and to Streptomyces coelicolor pyruvate dehydrogenase SC1A9.19 TR:Q9ZBT3 (EMBL:AL034446) (580 aa) fasta scores: E(): 1.4e-132, 56.62% id in 581 aa; Belongs to the TPP enzyme family.
   
    0.402
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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