STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0936Similar to Streptomyces coelicolor putative integral membrane transport protein SCC8A.02c TR:Q9KY46 (EMBL:AL356892) (689 aa) fasta scores: E(): 8.5e-70, 42.83% id in 523 aa, and to Mycobacterium tuberculosis CDC1551 drug transporter MT1926 TR:AAK46198 (EMBL:AE007049) (687 aa) fasta scores: E(): 1.1e-57, 37.45% id in 518 aa; Belongs to the major facilitator superfamily. (521 aa)    
Predicted Functional Partners:
DIP0937
Similar to Streptomyces coelicolor putative tetR-family transcriptional regulator SCF56.06 TR:Q9RD60 (EMBL:AL133424) (213 aa) fasta scores: E(): 4.4e-06, 35.59% id in 118 aa.
 
   
 0.874
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
       0.657
DIP0939
Similar to Streptomyces coelicolor conserved hypothetical protein SCK7.20c TR:Q9FBN2 (EMBL:AL391754) (343 aa) fasta scores: E(): 7.1e-79, 67.89% id in 327 aa, and to Escherichia coli protein GlpX or B3925 SW:GLPX_ECOLI (P28860) (336 aa) fasta scores: E(): 4.6e-39, 44.61% id in 325 aa.
       0.530
DIP0940
Putative membrane protein; Low similarity to Mycobacterium tuberculosis hypothetical 24.6 kDa protein Rv1100 or MTV017.53 TR:O53448 (EMBL:AL021897) (233 aa) fasta scores: E(): 8e-06, 28.92% id in 204 aa.
       0.471
DIP0272
Putative antibiotic resistance protein (membrane protein); Similar to Staphylococcus aureus SA0132 protein TR:Q99X78 (EMBL:AP003129) (450 aa) fasta scores: E(): 3.5e-67, 46.1% id in 436 aa, and to Bacillus subtilis tetracycline resistance protein TetB or Tet SW:TCRB_BACSU (P23054) (458 aa) fasta scores: E(): 1.3e-23, 26.3% id in 403 aa.
  
     0.411
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: medium (44%) [HD]