STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0950Putative oxidoreductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (297 aa)    
Predicted Functional Partners:
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
    
 0.926
DIP2365
Similar to Bacillus subtilis branched-chain amino acid transport protein AzlD SW:AZLD_BACSU (O07923) (110 aa) fasta scores: E(): 8.2e-05, 36.27% id in 102 aa.
   
    0.918
DIP1993
Conserved hypothetical protein; C-terminus is similar to the C-terminal region of Lotus japonicus pantoate--beta-alanine ligase precursor PanC SW:PANC_LOTJA (O24035) (307 aa) fasta scores: E(): 4.4e-07, 28.11% id in 217 aa. Similar to the Mycobacterium tuberculosis pantoate--beta-alanine ligase Rv3602c SW:PANC_MYCTU (O06280) (309 aa) fasta scores: E(): 4.7e-19, 38.62% id in 277 aa; Belongs to the pantothenate synthetase family.
    
 0.917
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
    
 0.917
DIP0133
Similar to Escherichia coli alkylated DNA repair protein Alkb or AidD or B2212 SW:ALKB_ECOLI (P05050) (216 aa) fasta scores: E(): 1.4e-12, 35.02% id in 237 aa.
   
    0.720
DIP0349
Similar to Streptomyces coelicolor putative DNA repair protein SCG20A.20c TR:Q9K3M0 (EMBL:AL360055) (216 aa) fasta scores: E(): 1.4e-27, 44.54% id in 220 aa, and to Escherichia coli alkylated DNA repair protein AlkB or AidD or B2212 SW:ALKB_ECOLI (P05050) (216 aa) fasta scores: E(): 5.6e-10, 32.46% id in 231 aa.
   
    0.720
DIP0951
Putative membrane protein; Similar to Bacillus subtilis YkoE TR:O34738 (EMBL:AJ002571) (199 aa) fasta scores: E(): 5.8e-16, 39.36% id in 188 aa.
 
     0.710
DIP0949
Putative ABC transport system membrane protein; Similar to Deinococcus radiodurans conserved hypothetical protein DR1297 TR:Q9RUT5 (EMBL:AE001977) (311 aa) fasta scores: E(): 2.2e-57, 51.92% id in 312 aa, and to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3176.1 TR:AAK47515 (EMBL:AE007134) (306 aa) fasta scores: E(): 5.1e-55, 54.54% id in 297 aa.
       0.700
DIP0954
Putative ABC transport system membrane protein; Low similarity to Bacillus subtilis YkoC TR:O34572 (EMBL:AJ002571) (254 aa) fasta scores: E(): 1.3e-06, 24.48% id in 241 aa.
 
     0.458
DIP0955
Hypothetical protein; No significant database matches.
 
     0.452
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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