Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DIP0951Putative membrane protein; Similar to Bacillus subtilis YkoE TR:O34738 (EMBL:AJ002571) (199 aa) fasta scores: E(): 5.8e-16, 39.36% id in 188 aa. (197 aa)    
Predicted Functional Partners:
DIP0954
Putative ABC transport system membrane protein; Low similarity to Bacillus subtilis YkoC TR:O34572 (EMBL:AJ002571) (254 aa) fasta scores: E(): 1.3e-06, 24.48% id in 241 aa.
 
  
 0.897
DIP0953
Putative ABC transport system ATP-binding protein; Similar to Staphylococcus aureus (strain N315) SA0928 protein or SAV1076 TR:BAB57238 (EMBL:AP003132) (466 aa) fasta scores: E(): 6.9e-32, 34.18% id in 433 aa.
 
    0.810
DIP0950
Putative oxidoreductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
 
     0.694
DIP2342
Similar to Streptomyces coelicolor putative integral membrane transport protein SCE87.11 SWALL:Q9RKC7 (EMBL:AL132674) (253 aa) fasta scores: E(): 0.082, 26.54% id in 226 aa.
 
  
 0.568
DIP0949
Putative ABC transport system membrane protein; Similar to Deinococcus radiodurans conserved hypothetical protein DR1297 TR:Q9RUT5 (EMBL:AE001977) (311 aa) fasta scores: E(): 2.2e-57, 51.92% id in 312 aa, and to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3176.1 TR:AAK47515 (EMBL:AE007134) (306 aa) fasta scores: E(): 5.1e-55, 54.54% id in 297 aa.
       0.558
DIP0955
Hypothetical protein; No significant database matches.
 
    0.547
DIP1664
Conserved hypothetical protein; Similar to Streptomyces coelicolor putative Mut-like protein 2SCG2.26c TR:Q9EX27 (EMBL:AL445963) (159 aa) fasta scores: E(): 1.3e-15, 46.7% id in 167 aa.
  
     0.532
thiC
Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
   
  
 0.515
DIP0883
Putative membrane protein; Low similarity to Escherichia coli protein PnuC or B0751 SW:PNUC_ECOLI (P31215) (239 aa) fasta scores: E(): 5e-07, 23.75% id in 240 aa.
  
   
 0.452
thiE
Putative thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.401
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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