Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
DIP0964Putative protease; Similar to Streptomyces coelicolor putative hydrolase SCBAC14E8.01c TR:Q9ADJ8 (EMBL:AL590435) (228 aa) fasta scores: E(): 0.0013, 30.47% id in 233 aa. (242 aa)    
Predicted Functional Partners:
DIP0966
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 hypothetical 16.6 kDa protein MT1668 TR:AAK45938 (EMBL:AE007030) (147 aa) fasta scores: E(): 1.1e-16, 39.43% id in 142 aa.
 
     0.858
DIP0967
Putative secreted protein; Similar to Mycobacterium tuberculosis CDC1551 hypothetical 36.6 kDa protein MT1193 TR:AAK45450 (EMBL:AE006997) (371 aa) fasta scores: E(): 7.8e-15, 33.91% id in 230 aa.
     
 0.838
arsC
Similar to Escherichia coli arsenate reductase ArsC or ArsG or B3503 SW:ARSC_ECOLI (P37311) (141 aa) fasta scores: E(): 1.8e-14, 48.24% id in 114 aa; Belongs to the ArsC family.
       0.836
DIP2269
Hypothetical protein; No significant database matches.
  
     0.658
DIP0555
Putative surface-anchored membrane protein; Very low similarity to Mycobacterium tuberculosis hypothetical protein Rv3448 or MTCY77.20 or MT3554 SWALL:O33354 (EMBL:Z95390) (467 aa) fasta scores: E(): 0.0016, 21.96% id in 478 aa. Note: Contains a putative sortase anchor site (LPNTG).
  
 
 
 0.618
DIP1826
Conserved hypothetical protein; Some similarity to Clostridium perfringens plasmid pCP13 hypothetical 28.2 kDa protein pcp29 TR:BAB62467 (EMBL:AP003515) (252 aa) fasta scores: E(): 1.4e-05, 27.513% id in 189 aa.
  
 
   0.519
DIP0867
Putative membrane protein; No significant database matches.
  
     0.496
esxA
Similar to Mycobacterium tuberculosis hypothetical 11.1 kDa protein Rv3444c or MTCY77.16c TR:O06261 (EMBL:Z95389) (100 aa) fasta scores: E(): 1e-08, 35.48% id in 93 aa; Belongs to the WXG100 family. ESAT-6 subfamily.
  
   0.495
DIP1934
Hypothetical protein; No significant database matches to the full length CDS. C-terminus is similar to the C-terminal regions of Streptomyces coelicolor putative secreted lipase SCD63A.10c TR:Q9KY65 (EMBL:AL356832) (331 aa) fasta scores: E(): 0.00018, 31.3% id in 214 aa, and Streptomyces coelicolor putative lipase 2SCG18.12c TR:Q9K3H5 (EMBL:AL390188) (289 aa) fasta scores: E(): 0.00064, 28.94% id in 190 aa.
  
     0.468
DIP0544
Putative secreted protein; Similar to Streptomyces coelicolor putative secreted protein 3SC5B7.14c TR:Q9EWT5 (EMBL:AL449216) (231 aa) fasta scores: E(): 9.9e-08, 30.99% id in 242 aa.
  
     0.466
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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