STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arsCSimilar to Escherichia coli arsenate reductase ArsC or ArsG or B3503 SW:ARSC_ECOLI (P37311) (141 aa) fasta scores: E(): 1.8e-14, 48.24% id in 114 aa; Belongs to the ArsC family. (114 aa)    
Predicted Functional Partners:
DIP0964
Putative protease; Similar to Streptomyces coelicolor putative hydrolase SCBAC14E8.01c TR:Q9ADJ8 (EMBL:AL590435) (228 aa) fasta scores: E(): 0.0013, 30.47% id in 233 aa.
       0.842
DIP0966
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 hypothetical 16.6 kDa protein MT1668 TR:AAK45938 (EMBL:AE007030) (147 aa) fasta scores: E(): 1.1e-16, 39.43% id in 142 aa.
       0.842
DIP0967
Putative secreted protein; Similar to Mycobacterium tuberculosis CDC1551 hypothetical 36.6 kDa protein MT1193 TR:AAK45450 (EMBL:AE006997) (371 aa) fasta scores: E(): 7.8e-15, 33.91% id in 230 aa.
       0.842
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.704
rpoC
DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.670
sigA
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
   0.606
sigB
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
    
   0.606
rpoZ
Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
   0.562
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.544
DIP0703
Putative oxidoreductase; Similar to Mycobacterium tuberculosis hypothetical 40.8 kDa protein Rv3230c or MTCY20B11.05c TR:O05875 (EMBL:Z95121) (380 aa) fasta scores: E(): 4.8e-60, 49.14% id in 350 aa, and to Escherichia coli NADH oxidoreductase Hcr or B0872 SW:HCR_ECOLI (P75824) (322 aa) fasta scores: E(): 1.9e-13, 28.71% id in 296 aa.
    
 
 0.469
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.